Fluoride has interesting properties related to human health, particularly in preventing dental
caries. However, when it is concentrated in drinking water at levels higher than 1 mg l− 1, a …

An All-Inclusive Guide to Surgical Techniques on RatsThe design of an adequate surgical
model, like the choice of the animal model itself, is extremely important for obtaining reliable …

Intestinal alkaline phosphatase (IAP) is a brush-border phosphomonoesterase. Its location
suggests an involvement in the uptake of nutrients, but its role has not yet been defined. IAP …

Bone deformation and fragility are common signs of skeletal fluorosis. Disorganisation of
bone tissue and presence of inflammatory foci were observed after fluoride (F−) …

Sodium fluoride (NaF) and sodium monofluorophosphate (MFP) are drugs used to increase
bone mass. They have been considered equivalent but the results of the treatments were not …

Alpha macroglobulins (AM) are plasma proteins whose main function is to inactivate
proteinases, protecting the tissues from the action of these enzymes. AM have influence on …

Intestinal alkaline phosphatase (IAP) is an enzyme of the brush border of the enterocyte. The
activity of IAP biphasically depends on calcium. Although calcium increases IAP activity …

Two fractions of rat intestinal alkaline phosphatase (IAP) were detected by Western blot:
168±6 and 475±45 kDa. The low molecular weight fraction constitutes 43% of the isolated …

Objective Osteoporosis is the consequence of an imbalance in bone remodeling caused by
excessive resorption or inappropriate bone formation. This paper proposes a sequential …

Fluorine is an element with no specific function in the human body, but has been assigned
beneficial and adverse effects on different systems. It has been shown that an adequate …