Delirium, a syndrome characterized by an acute change in attention, awareness and
cognition, is caused by a medical condition that cannot be better explained by a pre-existing …

Delirium is a debilitating form of brain dysfunction frequently encountered in the intensive
care unit (ICU). It is associated with increased morbidity and mortality, longer lengths of stay …

Background There are conflicting data on the effects of antipsychotic medications on
delirium in patients in the intensive care unit (ICU). Methods In a randomized, double-blind …

Importance Results of studies on use of prophylactic haloperidol in critically ill adults are
inconclusive, especially in patients at high risk of delirium. Objective To determine whether …

Objective: To revise the “Clinical Practice Guidelines for the Sustained Use of Sedatives and
Analgesics in the Critically Ill Adult” published in Critical Care Medicine in 2002. Methods …

Introduction Delirium is a frequent form of acute brain dysfunction in critically ill patients, and
several detection tools for it have been developed for use in the Intensive Care Unit (ICU) …

Objective: To test the hypothesis that duration of delirium in the intensive care unit is an
independent predictor of long-term cognitive impairment after critical illness requiring …

Context γ-Aminobutyric acid receptor agonist medications are the most commonly used
sedatives for intensive care unit (ICU) patients, yet preliminary evidence indicates that the α …

Context Protocolized sedation and daily sedation interruption are 2 strategies to minimize
sedation and reduce the duration of mechanical ventilation and intensive care unit (ICU) …

Background Delirium is frequently diagnosed in critically ill patients and is associated with
poor clinical outcomes. Haloperidol is the most commonly used drug for delirium despite …