Self-assembled stereomutation with supramolecular chirality inversion
G Liu, MG Humphrey, C Zhang, Y Zhao - Chemical Society Reviews, 2023 - pubs.rsc.org
Supramolecular chirality is involved not only in biological events such as gene
communication, replication, and enzyme catalysis but also in artificial self-assembly systems …
communication, replication, and enzyme catalysis but also in artificial self-assembly systems …
Infrared and Raman chemical imaging and spectroscopy at the nanoscale
The advent of nanotechnology, and the need to understand the chemical composition at the
nanoscale, has stimulated the convergence of IR and Raman spectroscopy with scanning …
nanoscale, has stimulated the convergence of IR and Raman spectroscopy with scanning …
Lipids uniquely alter the secondary structure and toxicity of amyloid beta 1–42 aggregates
Abrupt aggregation of amyloid β1‐42 (Aβ) peptide is a hallmark of Alzheimer's disease (AD),
a severe pathology that affects more than 44 million people worldwide. A growing body of …
a severe pathology that affects more than 44 million people worldwide. A growing body of …
Exploring the structure and formation mechanism of amyloid fibrils by Raman spectroscopy: a review
Amyloid fibrils are β-sheet rich protein aggregates that are strongly associated with various
neurodegenerative diseases. Raman spectroscopy has been broadly utilized to investigate …
neurodegenerative diseases. Raman spectroscopy has been broadly utilized to investigate …
Lipids uniquely alter rates of insulin aggregation and lower toxicity of amyloid aggregates
Amyloid formation is a hallmark of many medical diseases including diabetes type 2,
Alzheimer's and Parkinson diseases. Under these pathological conditions, misfolded …
Alzheimer's and Parkinson diseases. Under these pathological conditions, misfolded …
Structure of condensed phase peptides: insights from vibrational circular dichroism and Raman optical activity techniques
TA Keiderling - Chemical reviews, 2020 - ACS Publications
Peptides and proteins are naturally chiral molecular systems so that sensing their structure
and conformation with chirality-based spectral methods is an obvious and long-used …
and conformation with chirality-based spectral methods is an obvious and long-used …
Unsaturation in the fatty acids of phospholipids drastically alters the structure and toxicity of insulin aggregates grown in their presence
Lipid bilayers play an important role in the pathological assembly of amyloidogenic proteins
and peptides. This assembly yields oligomers and fibrils, which are highly toxic protein …
and peptides. This assembly yields oligomers and fibrils, which are highly toxic protein …
Chirality induction and amplification in supramolecular systems exhibiting vibrational optical activity
A Kaczor - Physical Chemistry Chemical Physics, 2023 - pubs.rsc.org
Vibrational optical activity (VOA) refers to two vibrational techniques: vibrational circular
dichroism (VCD) and Raman optical activity (ROA) that are sensitive both to the chirality and …
dichroism (VCD) and Raman optical activity (ROA) that are sensitive both to the chirality and …
The degree of unsaturation of fatty acids in phosphatidylserine alters the rate of insulin aggregation and the structure and toxicity of amyloid aggregates
Phosphatidylserine (PS) in the plasma membrane plays an important role in cell signaling
and apoptosis. Cell degeneration is also linked to numerous amyloid diseases, pathologies …
and apoptosis. Cell degeneration is also linked to numerous amyloid diseases, pathologies …
Length and unsaturation of fatty acids of phosphatidic acid determines the aggregation rate of insulin and modifies the structure and toxicity of insulin aggregates
Phosphatidic acid (PA) is a unique plasma membrane lipid that contains fatty acids (FAs)
with different lengths and degrees of unsaturation. Under physiological conditions, PA acts …
with different lengths and degrees of unsaturation. Under physiological conditions, PA acts …