Over the years biomedical research has been constantly oriented towards the development
of new therapeutics based on bioactive peptides and their analogues. In particular, the …

2-Azanorbornane – a versatile chiral aza-Diels–Alder cycloadduct: preparation, applications in
stereoselective synthesis and biological activity - Organic & Biomolecular Chemistry (RSC …

A practical synthesis of 2, 4-methanopyrrolidines was elaborated. The key synthetic step
was an intramolecular photochemical [2+ 2]-cycloaddition of an acrylic acid derivative in …

The first aminocatalyzed α‐alkylation of α‐branched aldehydes with benzyl bromides as
alkylating agents has been developed. Using a sterically demanding proline derived …

In an approach to the biologically important 6‐azabicyclo [3.2. 1] octane ring system, the
scope of the tandem 4‐exo‐trig carbamoyl radical cyclization—dithiocarbamate group …

The first fluorinated analogue of the naturally occurring 2, 4-methanoproline, 4-fluoro-2, 4-
methanoproline, has been synthesized in five steps from commercially available methyl 2 …

Practical syntheses of 2-azabicyclo [3.1. 1] heptane-1-carboxylic (2, 4-methanopipecolic), 2-
azabicyclo [2.2. 2] octane-1-carboxylic (2, 5-ethanopipecolic), and 9-azabicyclo [3.3. 1] …

Approaches to α-cyanopyrrolidines,-piperidines, and-azepanes, as well as their bi-and
polycyclic analogues are surveyed, which are based on Strecker reaction–intramolecular …

Differentiation of identical electrophilic functional groups (carboxylates) by a strategically
placed internal nucleophile (an amino group) in cyclic precursors was used as a key general …

A gram‐scale synthesis, physico‐chemical characterization, and lead‐likeness assessment
of 4‐di/trifluoromethyl‐2‐heterabicyclo [2.1. 1] hexanes as fluorinated bicyclic proline …