Cloud computing for genomic data analysis and collaboration

B Langmead, A Nellore - Nature Reviews Genetics, 2018‏ - nature.com
Next-generation sequencing has made major strides in the past decade. Studies based on
large sequencing data sets are growing in number, and public archives for raw sequencing …

Overview of breast cancer and implications of overtreatment of early-stage breast cancer: an Indian perspective

GS Bhattacharyya, DC Doval, CJ Desai… - JCO global …, 2020‏ - ascopubs.org
The prevalence and mortality of breast cancer is increasing in Asian countries, including
India. With advances in medical technology leading to better detection and characterization …

Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): explanation and elaboration

KGM Moons, DG Altman, JB Reitsma… - Annals of internal …, 2015‏ - acpjournals.org
The TRIPOD (Transparent Reporting of a multivariable prediction model for Individual
Prognosis Or Diagnosis) Statement includes a 22-item checklist, which aims to improve the …

Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer

C Isella, F Brundu, SE Bellomo, F Galimi… - Nature …, 2017‏ - nature.com
Stromal content heavily impacts the transcriptional classification of colorectal cancer (CRC),
with clinical and biological implications. Lineage-dependent stromal transcriptional …

[PDF][PDF] Characterization and proteome of circulating extracellular vesicles as potential biomarkers for NASH

D Povero, H Yamashita, W Ren… - Hepatology …, 2020‏ - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is currently one of most common forms of chronic
liver disease globally. NAFLD represents a wide spectrum of liver involvement from …

Meta-analytic support vector machine for integrating multiple omics data

SH Kim, JH Jhong, JJ Lee, JY Koo - BioData mining, 2017‏ - Springer
Background Of late, high-throughput microarray and sequencing data have been
extensively used to monitor biomarkers and biological processes related to many diseases …

Cancer cells enter an adaptive persistence to survive radiotherapy and repopulate tumor

Y Zhao, T Lu, Y Song, Y Wen, Z Deng, J Fan… - Advanced …, 2023‏ - Wiley Online Library
Repopulation of residual tumor cells impedes curative radiotherapy, yet the mechanism is
not fully understood. It is recently appreciated that cancer cells adopt a transient persistence …

[HTML][HTML] Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer: a systematic review and economic analysis

S Harnan, P Tappenden, K Cooper… - Health Technology …, 2019‏ - pmc.ncbi.nlm.nih.gov
BACKGROUND Breast cancer and its treatment can have an impact on health-related
quality of life and survival. Tumour profiling tests aim to identify whether or not women need …

GPR180 is a new member of the Golgi-dynamics domain seven-transmembrane helix protein family

SA Mitrovic, C Demalgiriya-Gamage, LM Winter… - Communications …, 2024‏ - nature.com
GOLD domain seven-transmembrane helix (GOST) proteins form a new protein family
involved in trafficking of membrane-associated cargo. They share a characteristic …

Incorporating prior biological knowledge for network-based differential gene expression analysis using differentially weighted graphical LASSO

Y Zuo, Y Cui, G Yu, R Li, HW Ressom - BMC bioinformatics, 2017‏ - Springer
Background Conventional differential gene expression analysis by methods such as
student'st-test, SAM, and Empirical Bayes often searches for statistically significant genes …