Cognitive deficits are a core feature of schizophrenia, account for much of the impaired
functioning associated with the disorder and are not responsive to existing treatments. In this …

Bipolar disorders are a complex group of severe and chronic disorders that includes bipolar
I disorder, defined by the presence of a syndromal, manic episode, and bipolar II disorder …

Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-
wide association study of 41,917 bipolar disorder cases and 371,549 controls of European …

Background Schizophrenia (SCZ) is a severe psychiatric disorder that involves inflammatory
processes. The aim of this study was to explore the field of inflammation-related research in …

Psychiatric genetics has made substantial progress in the last decade, providing new
insights into the genetic etiology of psychiatric disorders, and paving the way for precision …

Personality and cognitive function are heritable mental traits whose genetic foundations may
be distributed across interconnected brain functions. Previous studies have typically treated …

Schizophrenia is a severe psychiatric disorder with considerable morbidity and mortality.
Although the past two decades have seen limited improvement in the treatment of …

Evolutionary biology provides a crucial foundation for medicine and behavioral science that
has been missing from psychiatry. Its absence helps to explain slow progress; its advent …

In recent years, genome-wide association study (GWAS) sample sizes have become larger,
the statistical power has improved and thousands of trait-associated variants have been …

Schizophrenia occurs in about one in four individuals with 22q11. 2 deletion syndrome
(22q11. 2DS). The aim of this International Brain and Behavior 22q11. 2DS Consortium …