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The persistence and transience of memory
The predominant focus in the neurobiological study of memory has been on remembering
(persistence). However, recent studies have considered the neurobiology of forgetting …
(persistence). However, recent studies have considered the neurobiology of forgetting …
Decay happens: the role of active forgetting in memory
Although the biological bases of forgetting remain obscure, the consensus among cognitive
psychologists emphasizes interference processes, rejecting decay in accounting for memory …
psychologists emphasizes interference processes, rejecting decay in accounting for memory …
Adult neurogenesis: beyond learning and memory
New neurons continue to be generated in the dentate gyrus throughout life, providing this
region of the hippocampus with exceptional structural plasticity, but the function of this …
region of the hippocampus with exceptional structural plasticity, but the function of this …
Neurogenesis-mediated forgetting minimizes proactive interference
Established memories may interfere with the encoding of new memories, particularly when
existing and new memories overlap in content. By manipulating levels of hippocampal …
existing and new memories overlap in content. By manipulating levels of hippocampal …
Hippocampal neurogenesis and forgetting
The hippocampus is thought to automatically encode all experience, yet the vast majority of
our experiences are not remembered later. Although psychological theories have postulated …
our experiences are not remembered later. Although psychological theories have postulated …
Adult hippocampal neurogenesis, fear generalization, and stress
The generalization of fear is an adaptive, behavioral, and physiological response to the
likelihood of threat in the environment. In contrast, the overgeneralization of fear, a cardinal …
likelihood of threat in the environment. In contrast, the overgeneralization of fear, a cardinal …
Chemotherapy-induced cognitive impairment (CICI): An overview of etiology and pathogenesis
Many cancer patients treated with chemotherapy develop chemotherapy-induced cognitive
impairment (CICI), often referred to as chemo-brain, which manifest during or post-treatment …
impairment (CICI), often referred to as chemo-brain, which manifest during or post-treatment …
Adult‐born hippocampal neurons promote cognitive flexibility in mice
The hippocampus is involved in segregating memories, an ability that utilizes the neural
process of pattern separation and allows for cognitive flexibility. We evaluated a proposed …
process of pattern separation and allows for cognitive flexibility. We evaluated a proposed …
[HTML][HTML] Epigenetics of stress adaptations in the brain
Recent findings in epigenetics shed new light on the regulation of gene expression in the
central nervous system (CNS) during stress. The most frequently studied epigenetic …
central nervous system (CNS) during stress. The most frequently studied epigenetic …
Adult hippocampal neurogenesis reduces memory interference in humans: opposing effects of aerobic exercise and depression
Since the remarkable discovery of adult neurogenesis in the mammalian hippocampus,
considerable effort has been devoted to unraveling the functional significance of these new …
considerable effort has been devoted to unraveling the functional significance of these new …