The present review deals with current advances in the chemoenzymatic synthesis of
biologically important nucleoside analogues (NA), either by the use of microorganisms or …

Antiviral polymers are part of a major campaign led by the scientific community in recent
years. Facing this most demanding of campaigns, two main approaches have been …

The re-emerging Zika virus (ZIKV) is an arthropod-borne virus that has been described to
have explosive potential as a worldwide pandemic. The initial transmission of the virus was …

Severe acute respiratory syndrome–associated coronavirus 2 has caused a global public
health crisis with high rates of infection and mortality. Treatment and prevention approaches …

Synthetic polymers have unique properties as antibacterial and antiviral agents due to their
buffering effect for endosomal escape, high molecular weight, function, and tunable …

Prodrug monomers derived from the antibiotic ciprofloxacin were synthesized with phenolic
or aliphatic esters linking the drug to a polymerizable methacrylate group. RAFT …

Background: Poor pharmacokinetic profiles and resistance are the main two drawbacks from
which currently used antiviral agents suffer, thus make them excellent targets for research …

This review summarizes briefly literature reports on nucleoside analogues containing five-
membered aglycones based on imidazole-4-carboxamide, 1, 2, 4-triazole-3-carboxamide or …

Macromolecular (pro) drugs are a sub-discipline of medicinal and polymer chemistries
aiming to optimize the delivery of drugs to their site of action. In recent decades, this field of …

Human immunodeficiency virus (HIV) and hepatitis C virus (HCV) represent tremendous
healthcare burdens with a large proportion of patients hosting the two viruses at the same …