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Deep learning in drug discovery: an integrative review and future challenges
Recently, using artificial intelligence (AI) in drug discovery has received much attention
since it significantly shortens the time and cost of develo** new drugs. Deep learning (DL) …
since it significantly shortens the time and cost of develo** new drugs. Deep learning (DL) …
Artificial intelligence for drug discovery: Resources, methods, and applications
W Chen, X Liu, S Zhang, S Chen - Molecular therapy Nucleic acids, 2023 - cell.com
Conventional wet laboratory testing, validations, and synthetic procedures are costly and
time-consuming for drug discovery. Advancements in artificial intelligence (AI) techniques …
time-consuming for drug discovery. Advancements in artificial intelligence (AI) techniques …
Unlocking hidden potential: advancements, approaches, and obstacles in repurposing drugs for cancer therapy
FR Weth, GB Hoggarth, AF Weth, E Paterson… - British journal of …, 2024 - nature.com
High rates of failure, exorbitant costs, and the sluggish pace of new drug discovery and
development have led to a growing interest in repurposing “old” drugs to treat both common …
development have led to a growing interest in repurposing “old” drugs to treat both common …
Artificial intelligence in cancer target identification and drug discovery
Artificial intelligence is an advanced method to identify novel anticancer targets and discover
novel drugs from biology networks because the networks can effectively preserve and …
novel drugs from biology networks because the networks can effectively preserve and …
Nanocomposites based on lanthanide-doped upconversion nanoparticles: diverse designs and applications
K Du, J Feng, X Gao, H Zhang - Light: Science & Applications, 2022 - nature.com
Lanthanide-doped upconversion nanoparticles (UCNPs) have aroused extraordinary
interest due to the unique physical and chemical properties. Combining UCNPs with other …
interest due to the unique physical and chemical properties. Combining UCNPs with other …
Network medicine framework for identifying drug-repurposing opportunities for COVID-19
The COVID-19 pandemic has highlighted the need to quickly and reliably prioritize clinically
approved compounds for their potential effectiveness for severe acute respiratory syndrome …
approved compounds for their potential effectiveness for severe acute respiratory syndrome …
Concepts of artificial intelligence for computer-assisted drug discovery
X Yang, Y Wang, R Byrne, G Schneider… - Chemical …, 2019 - ACS Publications
Artificial intelligence (AI), and, in particular, deep learning as a subcategory of AI, provides
opportunities for the discovery and development of innovative drugs. Various machine …
opportunities for the discovery and development of innovative drugs. Various machine …
A review of computational drug repositioning: strategies, approaches, opportunities, challenges, and directions
Drug repositioning is the process of identifying novel therapeutic potentials for existing drugs
and discovering therapies for untreated diseases. Drug repositioning, therefore, plays an …
and discovering therapies for untreated diseases. Drug repositioning, therefore, plays an …
Extensive impact of non-antibiotic drugs on human gut bacteria
A few commonly used non-antibiotic drugs have recently been associated with changes in
gut microbiome composition, but the extent of this phenomenon is unknown. Here, we …
gut microbiome composition, but the extent of this phenomenon is unknown. Here, we …
Drug repurposing: progress, challenges and recommendations
Given the high attrition rates, substantial costs and slow pace of new drug discovery and
development, repurposing of'old'drugs to treat both common and rare diseases is …
development, repurposing of'old'drugs to treat both common and rare diseases is …