Exploring and understanding biological and pathological changes are of great significance
for early diagnosis and therapy of diseases. Optical sensing and imaging approaches have …

The design and use of materials in the nanoscale size range for addressing medical and
health-related issues continues to receive increasing interest. Research in nanomedicine …

We review the current state of optical methods for sensing oxygen. These have become
powerful alternatives to electrochemical detection and in the process of replacing the Clark …

Conspectus Although the interactions of transition metal complexes with biological
molecules have been extensively studied, the use of luminescent transition metal complexes …

Singlet oxygen, O2 (a1Δg), the lowest excited electronic state of molecular oxygen, has
been known to the scientific community for∼ 80 years. It has a characteristic chemistry that …

Fluorescence imaging techniques involving chemical sensors are essential tools in many
fields of science and technology because they enable the visualization of parameters which …

Luminescent materials are widely used for imaging and sensing owing to their high
sensitivity, rapid response and facile detection by many optical technologies. Typically …

We report the design of a phosphorescence/fluorescence dual-emissive nanoscale metal–
organic framework (NMOF), R-UiO, as an intracellular oxygen (O2) sensor. R-UiO contains a …

The invention generally relates to fluorescent nanoparticles and more specifically to silica-
based fluorescent nanopar ticles of less than 30 nm with covalently attached organic dyes …

(56) References Cited(57) ABSTRACT US PATENT DOCUMENTS Sensor particles
comprise a silica-based core and at least one 4,275,300 A* 6/1981 Abbott …