The study of innate immunity and its link to inflammation and host defense encompasses
diverse areas of biology, ranging from genetics and biophysics to signal transduction and …

Toll-like receptors (TLRs) play crucial roles in the innate immune system by recognizing
pathogen-associated molecular patterns derived from various microbes. TLRs signal …

Toll-like receptors (TLRs) are germline-encoded pattern recognition receptors (PRRs) that
play a central role in host cell recognition and responses to microbial pathogens. TLR …

Many of the ligands for Toll-like receptors (TLRs) are unique to microorganisms, such that
receptor activation unequivocally indicates the presence of something foreign. However, a …

Receptors of the innate immune system detect conserved determinants of microbial and viral
origin. Activation of these receptors initiates signaling events that culminate in an effective …

The immune system is a very diverse system of the host that evolved during evolution to
cope with various pathogens present in the vicinity of environmental surroundings inhabited …

Signal transduction by the Toll-like receptors (TLRs) is central to host defence against many
pathogenic microorganisms and also underlies a large burden of human disease. Thus, the …

Background/Aim. Toll‐like receptors (TLRs) are pivotal biomolecules in the immune system.
Today, we are all aware of the importance of TLRs in bridging innate and adaptive immune …

Abstract Toll-like receptor 3 (TLR3) is a member of the TLR family, mediating the
transcriptional induction of type I interferons (IFNs), proinflammatory cytokines, and …

Toll-like receptors (TLRs) serve as the body's first line of defense, recognizing both
pathogen-expressed molecules and host-derived molecules released from damaged or …