Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications

SM Dadfar, K Roemhild, NI Drude… - Advanced drug delivery …, 2019‏ - Elsevier
Many different iron oxide nanoparticles have been evaluated over the years, for a wide
variety of biomedical applications. We here summarize the synthesis, surface …

Spinel ferrite nanoparticles and nanocomposites for biomedical applications and their toxicity

KK Kefeni, TAM Msagati, TTI Nkambule… - Materials Science and …, 2020‏ - Elsevier
This review focuses on the biomedical applications and toxicity of spinel ferrite nanoparticles
(SFNPs) with more emphasis on the recently published work. A critical review is provided on …

Uptake, distribution, clearance, and toxicity of iron oxide nanoparticles with different sizes and coatings

Q Feng, Y Liu, J Huang, K Chen, J Huang, K **ao - Scientific reports, 2018‏ - nature.com
Iron oxide nanoparticles (IONPs) have been increasingly used in biomedical applications,
but the comprehensive understanding of their interactions with biological systems is …

Faster Mean-shift: GPU-accelerated clustering for cosine embedding-based cell segmentation and tracking

M Zhao, A Jha, Q Liu, BA Millis… - Medical Image …, 2021‏ - Elsevier
Recently, single-stage embedding based deep learning algorithms gain increasing attention
in cell segmentation and tracking. Compared with the traditional “segment-then-associate” …

Nanoparticles in magnetic resonance imaging: from simple to dual contrast agents

J Estelrich, MJ Sánchez-Martín… - International journal of …, 2015‏ - Taylor & Francis
Magnetic resonance imaging (MRI) has become one of the most widely used and powerful
tools for noninvasive clinical diagnosis owing to its high degree of soft tissue contrast, spatial …

Manganese oxide nanoparticles as MRI contrast agents in tumor multimodal imaging and therapy

X Cai, Q Zhu, Y Zeng, Q Zeng, X Chen… - International journal of …, 2019‏ - Taylor & Francis
Contrast agents (CAs) play a crucial role in high-quality magnetic resonance imaging (MRI)
applications. At present, as a result of the Gd-based CAs which are associated with renal …

Engineering of magnetic nanoparticles as magnetic particle imaging tracers

C Lu, L Han, J Wang, J Wan, G Song… - Chemical Society Reviews, 2021‏ - pubs.rsc.org
Magnetic particle imaging (MPI) has recently emerged as a promising non-invasive imaging
technique because of its signal linearly propotional to the tracer mass, ability to generate …

Imaging macrophages with nanoparticles

R Weissleder, M Nahrendorf, MJ Pittet - Nature materials, 2014‏ - nature.com
Nanomaterials have much to offer, not only in deciphering innate immune cell biology and
tracking cells, but also in advancing personalized clinical care by providing diagnostic and …

Reporter gene imaging of targeted T cell immunotherapy in recurrent glioma

KV Keu, TH Witney, S Yaghoubi, J Rosenberg… - Science translational …, 2017‏ - science.org
High-grade gliomas are aggressive cancers that often become rapidly fatal. Immunotherapy
using CD8+ cytotoxic T lymphocytes (CTLs), engineered to express both herpes simplex …

Tracking immune cells in vivo using magnetic resonance imaging

ET Ahrens, JWM Bulte - Nature Reviews Immunology, 2013‏ - nature.com
The increasing complexity of in vivo imaging technologies, coupled with the development of
cell therapies, has fuelled a revolution in immune cell tracking in vivo. Powerful magnetic …