At least 25 bioactive glass (BG) medical devices have been approved for clinical use by
global regulatory agencies. Diverse applications include monolithic implants, bone void …

Bioactive glasses caused a revolution in healthcare and paved the way for modern
biomaterial-driven regenerative medicine. The first 45S5 glass composition, invented by …

Metallic implants sometimes fail in orthopedic surgeries due to insufficient bio-functionality,
implant-associated infections, poor osteointegration due to high inertness (Ti, Co–Cr …

The discovery of bioactive glasses (BGs) in the late 1960s by Larry Hench et al. was driven
by the need for implant materials with an ability to bond to living tissues, which were …

Dental glass-ceramics (DGCs) are developed by controlled crystallization of oxide glasses
and form an important group of biomaterials used in modern dentistry. They are also of great …

Nowadays, bioactive glasses (BGs) are mainly used to improve and support the healing
process of osseous defects deriving from traumatic events, tumor removal, congenital …

Titanium (Ti) is broadly used for clinical purposes in various medical fields related to bone
repair because of its favorable mechanical properties and its ability to osseointegrate in host …

Metallic implant materials possess adequate mechanical properties such as strength, elastic
modulus, and ductility for long term support and stability in vivo. Traditional metallic …

Functionally graded materials (FGMs) are innovative materials whose composition and/or
microstructure gradually vary in space according to a designed law. As a result, also the …

Bioactive glasses are promising biomaterials for bone and tissue repair and reconstruction,
as they were shown to bond to both hard and soft tissues stimulating cells towards a path of …