Electrochemical methods for the analysis of clinically relevant biomolecules

M Labib, EH Sargent, SO Kelley - Chemical reviews, 2016 - ACS Publications
Rapid progress in identifying biomarkers that are hallmarks of disease has increased
demand for high-performance detection technologies. Implementation of electrochemical …

Real-Time, In Vivo Molecular Monitoring Using Electrochemical Aptamer Based Sensors: Opportunities and Challenges

AM Downs, KW Plaxco - ACS sensors, 2022 - ACS Publications
The continuous, real-time measurement of specific molecules in situ in the body would
greatly improve our ability to understand, diagnose, and treat disease. The vast majority of …

A flexible multiplexed immunosensor for point-of-care in situ wound monitoring

Y Gao, DT Nguyen, T Yeo, SB Lim, WX Tan… - Science …, 2021 - science.org
Chronic wounds arise from interruption of normal healing due to many potential
pathophysiological factors. Monitoring these multivariate factors can provide personalized …

Exosomes and nanoengineering: a match made for precision therapeutics

PHL Tran, D **ang, TTD Tran, W Yin… - Advanced …, 2020 - Wiley Online Library
Targeted exosomal delivery systems for precision nanomedicine attract wide interest across
areas of molecular cell biology, pharmaceutical sciences, and nanoengineering. Exosomes …

Development of an aptasensor for electrochemical detection of exosomes

Q Zhou, A Rahimian, K Son, DS Shin, T Patel, A Revzin - Methods, 2016 - Elsevier
Abstract Exosomes are small (50–100 nm in diameter) vesicles secreted from various
mammalian cells. Exosomes have been correlated with tumor antigens and anti-tumor …

Aptamers against pro-and anti-inflammatory cytokines: a review

M Boshtam, S Asgary, S Kouhpayeh, L Shariati… - Inflammation, 2017 - Springer
Inflammatory disorders result from continuous inflammation in injured sites. Many molecules
are involved in this process; the inhibition of which could prevent the inflammation …

Reagentless, structure-switching, electrochemical aptamer-based sensors

LR Schoukroun-Barnes, FC Macazo… - Annual Review of …, 2016 - annualreviews.org
The development of structure-switching, electrochemical, aptamer-based sensors over the
past∼ 10 years has led to a variety of reagentless sensors capable of analytical detection in …

Using cell membranes as recognition layers to construct ultrasensitive and selective bioelectronic affinity sensors

E Vargas, F Zhang, A Ben Hassine… - Journal of the …, 2022 - ACS Publications
Conventional sandwich immunosensors rely on antibody recognition layers to selectively
capture and detect target antigen analytes. However, the fabrication of these traditional …

Electrochemical sensing: A prognostic tool in the fight against COVID-19

S Kotru, M Klimuntowski, H Ridha, Z Uddin… - TrAC Trends in …, 2021 - Elsevier
The COVID-19 pandemic has devastated the world, despite all efforts in infection control and
treatment/vaccine development. Hospitals are currently overcrowded, with health statuses of …

Nucleic acid-based electrochemical biosensors for rapid clinical diagnosis: Advances, challenges, and opportunities

A Hashem, MAM Hossain, AR Marlinda… - Critical reviews in …, 2022 - Taylor & Francis
Clinical diagnostic tests should be quick, reliable, simple to perform, and affordable for
diagnosis and treatment of diseases. In this regard, owing to their novel properties …