Viruses are ubiquitous intracellular genetic parasites that heavily rely on the infected cell to
complete their replication life cycle. This dependency on the host machinery forces viruses …

The coevolution of host-pathogen interactions underlies many human physiological traits
associated with protection from or susceptibility to infections. Among the mechanisms that …

Quercetin, a bioflavonoid contained in several vegetables daily consumed, has been
studied for long time for its antiinflammatory and anticancer properties. Quercetin interacts …

Virus infection can trigger extrinsic apoptosis. Cell-surface death receptors of the tumor
necrosis factor family mediate this process. They either assist persistent viral infection or …

Since the discovery of cell apoptosis, other gene-regulated cell deaths are gradually
appreciated, including pyroptosis, ferroptosis, and necroptosis. Necroptosis is, so far, one of …

About a fifth of all human cancers worldwide are caused by infectious agents. In 12% of
cancers, seven different viruses have been causally linked to human oncogenesis: Epstein …

The linkage of Kaposi sarcoma (KS) to infection by a novel human herpesvirus (Kaposi
sarcoma–associated herpesvirus [KSHV]) is one of the great successes of contemporary …

Latency is a state of cryptic viral infection associated with genomic persistence and highly
restricted gene expression. Its hallmark is reversibility: under appropriate circumstances …

Kaposi's sarcoma had been recognized as unique human cancer for a century before it
manifested as an AIDS-defining illness with a suspected infectious etiology. The discovery of …

An important step in the herpesvirus life cycle is the switch from latency to lytic reactivation.
In order to study the life cycle of Kaposi's sarcoma-associated herpesvirus (KSHV), we …