Beyond their well-known functions in the acute phases of the immune response, neutrophils
play important roles in the various phases of tumor initiation and progression, through the …

There is an urgent need for new therapeutic strategies to contain the spread of the novel
coronavirus disease 2019 (COVID-19) and to curtail its most severe complications. Severely …

Severe COVID-19 patients develop acute respiratory distress syndrome that may progress to
cytokine storm syndrome, organ dysfunction, and death. Considering that neutrophil …

While neutrophil extracellular traps (NETs) are important for directly promoting cancer
growth, little is known about their impact on immune cells within the tumor microenvironment …

Human neutrophils, the most abundant circulating leukocytes, are fundamental components
of the host response against different pathogens. Until a few years ago, neutrophils received …

Severe influenza kills tens of thousands of individuals each year, yet the mechanisms
driving lethality in humans are poorly understood. Here we used a unique translational …

Background SARS-CoV-2 infection is associated with thrombotic and microvascular
complications. The cause of coagulopathy in the disease is incompletely understood …

Neutrophil extracellular traps (NET), formed by the extracellular release of decondensed
chromatin and granules, have been shown to promote tumor progression and metastasis …

Simple Summary Neutrophil Extracellular Traps (NETs) are formed following the activation
of neutrophils and play an important role in the development of cancer, especially metastatic …

Pancreatic ductal adenocarcinoma (PDAC) tumors are characterized by a desmoplastic
reaction resulting in dense deposition of collagen that is known to promote cancer …