Gastrointestinal transit time, glucose homeostasis and metabolic health: modulation by dietary fibers

M Müller, EE Canfora, EE Blaak - Nutrients, 2018 - mdpi.com
Gastrointestinal transit time may be an important determinant of glucose homeostasis and
metabolic health through effects on nutrient absorption and microbial composition, among …

Amylin: pharmacology, physiology, and clinical potential

DL Hay, S Chen, TA Lutz, DG Parkes, JD Roth… - Pharmacological …, 2015 - Elsevier
Amylin is a pancreatic β-cell hormone that produces effects in several different organ
systems. Here, we review the literature in rodents and in humans on amylin research since …

Dietary fiber supplements: effects in obesity and metabolic syndrome and relationship to gastrointestinal functions

A Papathanasopoulos, M Camilleri - Gastroenterology, 2010 - Elsevier
Dietary fiber is a term that reflects a heterogeneous group of natural food sources,
processed grains, and commercial supplements. Several forms of dietary fiber have been …

Relationships between gastric emptying, postprandial glycemia, and incretin hormones

CS Marathe, CK Rayner, KL Jones, M Horowitz - Diabetes care, 2013 - Am Diabetes Assoc
The importance of achieving tight glycemic control, usually assessed by glycated
hemoglobin (HbA1c), for both the prevention and delay in the progression of diabetes …

Relationships of upper gastrointestinal motor and sensory function with glycemic control

CK Rayner, M Samsom, KL Jones, M Horowitz - Diabetes care, 2001 - Am Diabetes Assoc
Acute changes in the blood glucose concentration have a major reversible effect on
esophageal, gastric, intestinal, gallbladder, and anorectal motility in both healthy subjects …

Gastric emptying and glycaemia in health and diabetes mellitus

LK Phillips, AM Deane, KL Jones, CK Rayner… - Nature Reviews …, 2015 - nature.com
The rate of gastric emptying is a critical determinant of postprandial glycaemia and,
accordingly, is fundamental to maintaining blood glucose homeostasis. Disordered gastric …

Effects of fat on gastric emptying of and the glycemic, insulin, and incretin responses to a carbohydrate meal in type 2 diabetes

D Gentilcore, R Chaikomin, KL Jones… - The Journal of …, 2006 - academic.oup.com
Context: Gastric emptying (GE) is a major determinant of postprandial glycemia. Because
the presence of fat in the small intestine inhibits GE, ingestion of fat may attenuate the …

Risk of gastroparesis in subjects with type 1 and 2 diabetes in the general population

RG Locke III, CD Schleck, AR Zinsmeister… - Official journal of the …, 2012 - journals.lww.com
OBJECTIVES: In patients with diabetes mellitus (DM) and upper gastrointestinal symptoms,
a diagnosis of diabetic gastroparesis is often considered, but population-based data on the …

Roles of the gut in glucose homeostasis

JJ Holst, F Gribble, M Horowitz, CK Rayner - Diabetes care, 2016 - Am Diabetes Assoc
The gastrointestinal tract plays a major role in the regulation of postprandial glucose profiles.
Gastric emptying is a highly regulated process, which normally ensures a limited and fairly …

Gastric emptying in diabetes: clinical significance and treatment

M Horowitz, D O'donovan, KL Jones, C Feinle… - Diabetic …, 2002 - Wiley Online Library
The outcome of recent studies has led to redefinition of concepts relating to the prevalence,
pathogenesis and clinical significance of disordered gastric emptying in patients with …