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Mechanisms of SARS-CoV-2 entry into cells
The unprecedented public health and economic impact of the COVID-19 pandemic caused
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …
Molecular mechanism of interaction between SARS-CoV-2 and host cells and interventional therapy
The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in an unprecedented setback …
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in an unprecedented setback …
SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity
SARS-CoV-2 variants with spike (S)-protein D614G mutations now predominate globally.
We therefore compare the properties of the mutated S protein (SG614) with the original …
We therefore compare the properties of the mutated S protein (SG614) with the original …
COVID-19 and cardiovascular disease: from bench to bedside
A pandemic of historic impact, coronavirus disease 2019 (COVID-19) has potential
consequences on the cardiovascular health of millions of people who survive infection …
consequences on the cardiovascular health of millions of people who survive infection …
Cathepsin L plays a key role in SARS-CoV-2 infection in humans and humanized mice and is a promising target for new drug development
To discover new drugs to combat COVID-19, an understanding of the molecular basis of
SARS-CoV-2 infection is urgently needed. Here, for the first time, we report the crucial role of …
SARS-CoV-2 infection is urgently needed. Here, for the first time, we report the crucial role of …
[HTML][HTML] Genome-wide CRISPR screens reveal host factors critical for SARS-CoV-2 infection
Identification of host genes essential for severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection may reveal novel therapeutic targets and inform our understanding …
(SARS-CoV-2) infection may reveal novel therapeutic targets and inform our understanding …
The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity
SARS coronavirus 2 (SARS-CoV-2) isolates encoding a D614G mutation in the viral spike
(S) protein predominate over time in locales where it is found, implying that this change …
(S) protein predominate over time in locales where it is found, implying that this change …
Coronavirus membrane fusion mechanism offers a potential target for antiviral development
Abstract The coronavirus disease 2019 (COVID-19) pandemic has focused attention on the
need to develop effective therapies against the causative agent, SARS-CoV-2, and also …
need to develop effective therapies against the causative agent, SARS-CoV-2, and also …
Natural product-derived phytochemicals as potential agents against coronaviruses: A review
Coronaviruses are responsible for a growing economic, social and mortality burden, as the
causative agent of diseases such as severe acute respiratory syndrome (SARS), Middle …
causative agent of diseases such as severe acute respiratory syndrome (SARS), Middle …
COVID-19 outbreak: history, mechanism, transmission, structural studies and therapeutics
Purpose The coronavirus outbreak emerged as a severe pandemic, claiming more than 0.8
million lives across the world and raised a major global health concern. We survey the …
million lives across the world and raised a major global health concern. We survey the …