The genomic landscape of African populations in health and disease

CN Rotimi, AR Bentley, AP Doumatey… - Human molecular …, 2017 - academic.oup.com
A deeper appreciation of the complex architecture of African genomes is critical to the global
effort to understand human history, biology and differential distribution of disease by …

Diversity and inclusion in genomic research: why the uneven progress?

AR Bentley, S Callier, CN Rotimi - Journal of community genetics, 2017 - Springer
Conducting genomic research in diverse populations has led to numerous advances in our
understanding of human history, biology, and health disparities, in addition to discoveries of …

[HTML][HTML] Climate change, biodiversity, ticks and tick-borne diseases: The butterfly effect

F Dantas-Torres - International Journal for Parasitology: parasites and …, 2015 - Elsevier
We have killed wild animals for obtaining food and decimated forests for many reasons.
Nowadays, we are burning fossil fuels as never before and even exploring petroleum in …

[HTML][HTML] The African diaspora: history, adaptation and health

CN Rotimi, F Tekola-Ayele, JL Baker… - Current opinion in genetics …, 2016 - Elsevier
The trans-Atlantic slave trade brought millions of Africans to the New World. Advances in
genomics are providing novel insights into the history and health of Africans and the …

Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans

A Choudhury, M Ramsay, S Hazelhurst, S Aron… - Nature …, 2017 - nature.com
Abstract The Southern African Human Genome Programme is a national initiative that
aspires to unlock the unique genetic character of southern African populations for a better …

Evidence for late Pleistocene origin of Astyanax mexicanus cavefish

J Fumey, H Hinaux, C Noirot, C Thermes… - BMC evolutionary …, 2018 - Springer
Background Cavefish populations belonging to the Mexican tetra species Astyanax
mexicanus are outstanding models to study the tempo and mode of adaptation to a radical …

Indigenous Arabs are descendants of the earliest split from ancient Eurasian populations

JL Rodriguez-Flores, K Fakhro, F Agosto-Perez… - Genome …, 2016 - genome.cshlp.org
An open question in the history of human migration is the identity of the earliest Eurasian
populations that have left contemporary descendants. The Arabian Peninsula was the initial …

GADMA: Genetic algorithm for inferring demographic history of multiple populations from allele frequency spectrum data

E Noskova, V Ulyantsev, KP Koepfli, SJ O'brien… - …, 2020 - academic.oup.com
Background The demographic history of any population is imprinted in the genomes of the
individuals that make up the population. One of the most popular and convenient …

Human ancestry correlates with language and reveals that race is not an objective genomic classifier

JL Baker, CN Rotimi, D Shriner - Scientific Reports, 2017 - nature.com
Genetic and archaeological studies have established a sub-Saharan African origin for
anatomically modern humans with subsequent migrations out of Africa. Using the largest …

An Improved Fst Estimator

G Chen, A Yuan, D Shriner, F Tekola-Ayele, J Zhou… - Plos one, 2015 - journals.plos.org
The fixation index F st plays a central role in ecological and evolutionary genetic studies.
The estimators of Wright (F^ st 1), Weir and Cockerham (F^ st 2), and Hudson et al.(F^ st 3) …