Lipid nanoparticles for the posterior eye segment
This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles,
Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective drug carriers for …
Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective drug carriers for …
Lipid nanoparticles (SLN, NLC): Overcoming the anatomical and physiological barriers of the eye–Part II-Ocular drug-loaded lipid nanoparticles
E Sánchez-López, M Espina, S Doktorovova… - European Journal of …, 2017 - Elsevier
In the recent decades, various controlled delivery systems have been introduced with the
aim to improve solubility, stability and bioavailability of poorly absorbed drugs. Among all …
aim to improve solubility, stability and bioavailability of poorly absorbed drugs. Among all …
Nanoemulsion as a feasible and biocompatible carrier for ocular delivery of travoprost: Improved pharmacokinetic/pharmacodynamic properties
A Ismail, M Nasr, O Sammour - International journal of pharmaceutics, 2020 - Elsevier
Travoprost is a synthetic prostaglandin F2α analogue used in treatment of glaucoma. Due to
its water insolubility and oily nature, novel delivery systems need to be developed to …
its water insolubility and oily nature, novel delivery systems need to be developed to …
Nanotherapies for the treatment of ocular diseases
S Reimondez-Troitiño, N Csaba, MJ Alonso… - European Journal of …, 2015 - Elsevier
The topical route is the most frequent and preferred way to deliver drugs to the eye.
Unfortunately, the very low ocular drug bioavailability (less than 5%) associated with this …
Unfortunately, the very low ocular drug bioavailability (less than 5%) associated with this …
Lipid-based nanocarriers for ophthalmic administration: towards experimental design implementation
FM González-Fernández, A Bianchera, P Gasco… - Pharmaceutics, 2021 - mdpi.com
Nanotherapeutics based on biocompatible lipid matrices allow for enhanced solubility of
poorly soluble compounds in the treatment of ophthalmic diseases, overcoming the …
poorly soluble compounds in the treatment of ophthalmic diseases, overcoming the …
Topical delivery of ocular therapeutics: carrier systems and physical methods
JG Souza, K Dias, TA Pereira… - Journal of Pharmacy …, 2014 - academic.oup.com
Objective The basic concepts, major mechanisms, technological developments and
advantages of the topical application of lipid-based systems (microemulsions …
advantages of the topical application of lipid-based systems (microemulsions …
Lipid-based nanocarriers challenging the ocular biological barriers: Current paradigm and future perspectives
Eye is the most specialized and sensory body organ and treating eye diseases efficiently is
necessary. Despite various attempts, the design of a consummate ophthalmic drug delivery …
necessary. Despite various attempts, the design of a consummate ophthalmic drug delivery …
Moxifloxacin loaded gelatin nanoparticles for ocular delivery: Formulation and in-vitro, in-vivo evaluation
The current research focuses on develo** positively charged gelatin nanoparticles loaded
with moxifloxacin for its effective ocular delivery and controlled release in corneal eye layer …
with moxifloxacin for its effective ocular delivery and controlled release in corneal eye layer …
Artificial neural network based particle size prediction of polymeric nanoparticles
Particle size of nanoparticles and the respective polydispersity are key factors influencing
their biopharmaceutical behavior in a large variety of therapeutic applications. Predicting …
their biopharmaceutical behavior in a large variety of therapeutic applications. Predicting …
Triamcinolone acetonide loaded-cationic nano-lipoidal formulation for uveitis: Evidences of improved biopharmaceutical performance and anti-inflammatory activity
Topical administration of corticosteroids is the cornerstone treatment of anterior uveitis, but
poor corneal penetration and retention cause hindrance in their therapeutic utility. The …
poor corneal penetration and retention cause hindrance in their therapeutic utility. The …