Ecologically mediated selection against hybrids, caused by hybrid phenotypes fitting poorly
into available niches, is typically viewed as distinct from selection caused by epistatic …

INTRODUCTION Genetic interactions occur when mutations in different genes combine to
result in a phenotype that is different from expectation based on those of the individual …

Interactions between alleles and across environments play an important role in the fitness of
hybrids and are at the heart of the speciation process. Fitness landscapes capture these …

The genomic era has made clear that introgression, or the movement of genetic material
between species, is a common feature of evolution. Examples of both adaptive and …

Theory building is an integral part of biological research, in general, and of speciation
research, in particular. Here, I review the modeling work on speciation done in the last 10 …

The evolution of postzygotic reproductive isolation is an important component of speciation.
But before isolation is complete there is sometimes a phase of heterosis in which hybrid …

Genetic incompatibilities are an important component of reproductive isolation. Although
theoretical studies have addressed their evolution, little is known about their maintenance …

All genes interact with other genes, and their additive effects and epistatic interactions affect
an organism's phenotype and fitness. Recent theoretical and empirical work has advanced …

Hybrids between species are often sterile or inviable. This form of reproductive isolation is
thought to evolve via the accumulation of mutations that interact to reduce fitness when …

The genomic architecture of functionally important traits is key to understanding the
maintenance of reproductive barriers and trait differences when divergent populations or …