Abstract limma is an R/Bioconductor software package that provides an integrated solution
for analysing data from gene expression experiments. It contains rich features for handling …

The extracellular matrix (ECM) is a fundamental component of multicellular organisms that
provides mechanical and chemical cues that orchestrate cellular and tissue organization …

The prediction of transcription factor (TF) activities from the gene expression of their targets
(ie, TF regulon) is becoming a widely used approach to characterize the functional status of …

Comprehensive multiplatform analysis of 80 uveal melanomas (UM) identifies four
molecularly distinct, clinically relevant subtypes: two associated with poor-prognosis …

Abstract The Ensembl Variant Effect Predictor is a powerful toolset for the analysis,
annotation, and prioritization of genomic variants in coding and non-coding regions. It …

Interactions between proteins and small molecules are an integral part of biological
processes in living organisms. Information on these interactions is dispersed over many …

We present a human miRNA tissue atlas by determining the abundance of 1997 miRNAs in
61 tissue biopsies of different organs from two individuals collected post-mortem. One …

Abstract The Ensembl project (http://www. ensembl. org) is a system for genome annotation,
analysis, storage and dissemination designed to facilitate the access of genomic annotation …

Small non-coding RNAs (sncRNAs) are pervasive regulators of physiological and
pathological processes. We previously developed the human miRNA Tissue Atlas, detailing …

Next-generation sequencing has made major strides in the past decade. Studies based on
large sequencing data sets are growing in number, and public archives for raw sequencing …