Phospholipids represent a crucial component for the structure of cell membranes.
Phosphatidylcholine and phosphatidylethanolamine are two phospholipids that comprise …

Significance This third biennial intraoperative molecular imaging (IMI) conference shows
how optical contrast agents have been applied to develop clinically significant endpoints …

Intraoperative molecular imaging (IMI) has recently emerged as an important tool in the
armamentarium of surgical oncologists. IMI allows real-time assessment of oncologic …

The tumor heterogeneity, which leads to individual variations in tumor microenvironments,
causes poor prognoses and limits therapeutic response. Emerging technology such as …

Abstract The WMIS Education Committee (2019–2022) reached a consensus that white
papers on molecular imaging could be beneficial for practitioners of molecular imaging at …

Upregulated choline metabolism, characterized by an increase in phosphocholine (PCho),
is a hallmark of oncogenesis and tumor progression. Choline kinase (ChoK), the enzyme …

Choline kinase (ChoK) is the first enzyme of the Kennedy pathway leading to the
biosynthesis of phosphatidylcholine (PtdCho), the most abundant phospholipid in eukaryotic …

Choline, a quintessential quaternary ammonium compound, plays a cardinal role in several
pivotal biological mechanisms, chiefly in safeguarding cell membrane integrity, orchestrating …

Choline kinase (ChoK) is a cytosolic enzyme that catalyzes the phosphorylation of choline to
form phosphorylcholine (P Cho) in the presence of ATP and magnesium. ChoK is required …

Methods for molecular imaging of target areas, including optical imaging, radionuclide
imaging, magnetic resonance imaging and other imaging technologies, are helpful for the …