How protons pave the way to aggressive cancers

P Swietach, E Boedtkjer, SF Pedersen - Nature Reviews Cancer, 2023 - nature.com
Cancers undergo sequential changes to proton (H+) concentration and sensing that are
consequences of the disease and facilitate its further progression. The impact of protonation …

7 Tesla and beyond: advanced methods and clinical applications in magnetic resonance imaging

T Platt, ME Ladd, D Paech - Investigative radiology, 2021 - journals.lww.com
Ultrahigh magnetic fields offer significantly higher signal-to-noise ratio, and several
magnetic resonance applications additionally benefit from a higher contrast-to-noise ratio …

SARS-CoV-2 infection of human neurons is TMPRSS2 independent, requires endosomal cell entry, and can be blocked by inhibitors of host phosphoinositol-5 kinase

P Kettunen, A Lesnikova, N Räsänen, R Ojha… - Journal of …, 2023 - journals.asm.org
ABSTRACT 2019 coronavirus disease (COVID-19) is a disease caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). In addition to respiratory illness, COVID …

Stereotactic magnetic resonance-guided adaptive and non-adaptive radiotherapy on combination MR-linear accelerators: current practice and future directions

JM Bryant, J Weygand, E Keit, R Cruz-Chamorro… - Cancers, 2023 - mdpi.com
Simple Summary Stereotactic body radiotherapy (SBRT) is an effective radiation therapy
technique that heavily relies upon daily image guidance to achieve the necessary precision …

High-grade glioma treatment response monitoring biomarkers: a position statement on the evidence supporting the use of advanced MRI techniques in the clinic, and …

TC Booth, EC Wiegers, EAH Warnert… - Frontiers in …, 2022 - frontiersin.org
Objective To summarize evidence for use of advanced MRI techniques as monitoring
biomarkers in the clinic, and to highlight the latest bench-to-bedside developments. Methods …

Deuterium echo‐planar spectroscopic imaging (EPSI) in the human liver in vivo at 7 T

KM Nam, A Gursan, AA Bhogal… - Magnetic …, 2023 - Wiley Online Library
Purpose To demonstrate the feasibility of deuterium echo‐planar spectroscopic imaging
(EPSI) to accelerate 3D deuterium metabolic imaging in the human liver at 7 T. Methods A …

Detection of tissue pH with quantitative chemical exchange saturation transfer magnetic resonance imaging

T Igarashi, H Kim, PZ Sun - NMR in Biomedicine, 2023 - Wiley Online Library
Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) has
emerged as a novel means for sensitive detection of dilute labile protons and chemical …

[HTML][HTML] Emerging methods and applications of ultra-high field MR spectroscopic imaging in the human brain

G Hangel, E Niess, P Lazen, P Bednarik, W Bogner… - Analytical …, 2022 - Elsevier
Abstract Magnetic Resonance Spectroscopic Imaging (MRSI) of the brain enables insights
into the metabolic changes and fluxes in diseases such as tumors, multiple sclerosis …

[HTML][HTML] Imaging and treatment of brain tumors through molecular targeting: Recent clinical advances

F Zaccagna, JT Grist, N Quartuccio, F Riemer… - European Journal of …, 2021 - Elsevier
Molecular imaging techniques have rapidly progressed over recent decades providing
unprecedented in vivo characterization of metabolic pathways and molecular biomarkers …

Liquid-based encapsulation for implantable bioelectronics across broad pH environments

H Sun, X Xue, GL Robilotto, X Zhang, CH Son… - Nature …, 2025 - nature.com
Wearable and implantable bioelectronics that can interface for extended periods with highly
mobile organs and tissues across a broad pH range would be useful for various applications …