Cytochrome c, a protein that belongs to class 1 of the c-type cytochrome family, exerts
different functions depending on its cellular localization and the conditions in which it …

Cytochrome c (cyt c) is a small soluble heme protein characterized by a relatively flexible
structure, particularly in the ferric form, such that it is able to sample a broad conformational …

In response to many apoptotic stimuli, oligomerization of Bax is essential for mitochondrial
outer membrane permeabilization and the ensuing release of cytochrome c. These events …

Recently, phospholipid peroxidation products gained a reputation as key regulatory
molecules and participants in oxidative signaling pathways. During apoptosis, a …

Biological macromolecules evolved to perform their function in specific cellular environment
(subcellular compartments or tissues); therefore, they should be adapted to the biophysical …

Microbes are ubiquitously distributed in nature and are a critical part of the holobiont fitness.
They are perceived as the most potential biochemical reservoir of inordinately diverse and …

Interactions of cytochrome c (cyt c) with cardiolipin (CL) are important for both electron
transfer and apoptotic functions of this protein. A sluggish peroxidase in its native state …

Cytochrome c (cyt c) is a cationic hemoprotein of∼ 100 amino acid residues that exhibits
exceptional functional versatility. While its primary function is electron transfer in the …

Cardiolipins (CL) represent unique phospholipids of bacteria and eukaryotic mitochondria
with four acyl chains and two phosphate groups that have been implicated in numerous …

Cardiolipin (CL) is a unique dimeric phospholipid that exists almost exclusively in the inner
mitochondrial membrane (IMM) in eukaryotic cells. Two chiral carbons and four fatty acyl …