To facilitate clinical trials of disease-modifying therapies for Alzheimer's disease, which are
expected to be most efficacious at the earliest and mildest stages of the disease,, supportive …

With the objective to formulate multifunctional nanosized liposomes to target amyloid
deposits in Alzheimer Disease (AD) brains, a lipid–PEG–curcumin derivative was …

The effect of various types of nanoliposomes (associated with curcumin, phosphatidic acid,
cardiolipin, or GM1 ganglioside) on the aggregation of the amyloid-β1-42 (Aβ1-42) peptide …

The formation of β-amyloid (Aβ) deposits in the brain is likely to be a seminal step in the
development of Alzheimer's disease. Recent studies support the hypothesis that Aβ soluble …

According to the" amyloid cascade" hypothesis of Alzheimer disease, the formation of Aβ
fibrils and senile plaques in the brain initiates a cascade of events leading to the formation of …

To identify food and beverages that provide the regular intake of natural compounds
capable of interfering with toxic amyloidogenic aggregates, we developed an experimental …

Their physicochemical properties and relatively low cost make cellulose nanocrystals
(CNCs) a potential candidate for future large-scale production in many fields including …

The relevant social and economic costs associated with aging and neurodegenerative
diseases, particularly Alzheimer's disease (AD), entail considerable efforts to develop …

The cellular prion protein (PrP C), which is highly expressed at synapses, was identified as a
receptor for the amyloid-β (Aβ) oligomers that are associated with dementia in Alzheimer …

We recently reported a novel Aβ precursor protein mutation (A673V), corresponding to
position 2 of Aβ1–42 peptides (Aβ1–42 A2V), that caused an early onset AD-type dementia …