Factors influencing peak bone mass gain

X Zhu, H Zheng - Frontiers of medicine, 2021 - Springer
Bone mass is a key determinant of osteoporosis and fragility fractures. Epidemiologic
studies have shown that a 10% increase in peak bone mass (PBM) at the population level …

Influence of body weight on bone mass, architecture and turnover

UT Iwaniec, RT Turner - Journal of Endocrinology, 2016 - joe.bioscientifica.com
Aldosterone, secreted by the adrenal zona glomerulosa, enhances sodium retention, thus
increasing blood volume and pressure. Excessive production of aldosterone results in high …

Biomechanics, obesity, and osteoarthritis. The role of adipokines: When the levee breaks

V Francisco, T Pérez, J Pino, V López… - Journal of …, 2018 - Wiley Online Library
Osteoarthritis is a high‐incidence painful and debilitating disease characterized by
progressive degeneration of articular joints, which indicates a breakdown in joint …

The bones of children with obesity

D Fintini, S Cianfarani, M Cofini, A Andreoletti… - Frontiers in …, 2020 - frontiersin.org
Excess adiposity in childhood may affect bone development, ultimately leading to bone
frailty. Previous reports showing an increased rate of extremity fractures in children with …

Cellular and molecular mechanisms associating obesity to bone loss

YS Forte, M Renovato-Martins, C Barja-Fidalgo - Cells, 2023 - mdpi.com
Obesity is an alarming disease that favors the upset of other illnesses and enhances
mortality. It is spreading fast worldwide may affect more than 1 billion people by 2030. The …

Peripheral quantitative computed tomography (pQCT) for the assessment of bone strength in most of bone affecting conditions in developmental age: a review

S Stagi, L Cavalli, T Cavalli, M de Martino… - Italian journal of …, 2016 - Springer
Peripheral quantitative computed tomography provides an automatical scan analysis of
trabecular and cortical bone compartments, calculating not only their bone mineral density …

Changes in skeletal integrity and marrow adiposity during high-fat diet and after weight loss

EL Scheller, B Khoury, KL Moller, NKY Wee… - Frontiers in …, 2016 - frontiersin.org
The prevalence of obesity has continued to rise over the past three decades leading to
significant increases in obesity-related medical care costs from metabolic and non-metabolic …

Differences in bone mineral density between normal‐weight children and children with overweight and obesity: a systematic review and meta‐analysis

J van Leeuwen, BW Koes, WD Paulis… - Obesity …, 2017 - Wiley Online Library
Objective This study examines the differences in bone mineral density between normal‐
weight children and children with overweight or obesity. Methods A systematic review and …

The impact of fat and obesity on bone microarchitecture and strength in children

JN Farr, P Dimitri - Calcified tissue international, 2017 - Springer
A complex interplay of genetic, environmental, hormonal, and behavioral factors affect
skeletal development, several of which are associated with childhood fractures. Given the …

Nonalcoholic fatty liver disease and decreased bone mineral density: is there a link?

G Targher, A Lonardo, M Rossini - Journal of Endocrinological …, 2015 - Springer
Purpose Liver diseases are associated with decreased bone mineral density (BMD) and
evidence suggests that nonalcoholic fatty liver disease (NAFLD) affects several extra …