The precision prevention and therapy of HPV‐related cervical cancer: new concepts and clinical implications
Cervical cancer is the third most common cancer in women worldwide, with concepts and
knowledge about its prevention and treatment evolving rapidly. Human papillomavirus …
knowledge about its prevention and treatment evolving rapidly. Human papillomavirus …
Clinical implications of (epi) genetic changes in HPV-induced cervical precancerous lesions
RDM Steenbergen, PJF Snijders… - Nature Reviews …, 2014 - nature.com
Infection of cervical epithelium with high-risk human papilloma virus (hrHPV) might result in
productive or transforming cervical intraepithelial neoplasia (CIN) lesions, the morphology of …
productive or transforming cervical intraepithelial neoplasia (CIN) lesions, the morphology of …
Cervical cancer risk for women undergoing concurrent testing for human papillomavirus and cervical cytology: a population-based study in routine clinical practice
HA Katki, WK Kinney, B Fetterman, T Lorey… - The lancet …, 2011 - thelancet.com
Background Concurrent testing for human papillomavirus (HPV) and cervical cytology (co-
testing) is an approved alternative to cytology alone in women aged 30 years and older. We …
testing) is an approved alternative to cytology alone in women aged 30 years and older. We …
Eurogin roadmap 2017: triage strategies for the management of HPV‐positive women in cervical screening programs
Cervical cancer screening will rely, increasingly, on HPV testing as a primary screen. The
requirement for triage tests which can delineate clinically significant infection is thus …
requirement for triage tests which can delineate clinically significant infection is thus …
Performance of DNA methylation assays for detection of high-grade cervical intraepithelial neoplasia (CIN2+): a systematic review and meta-analysis
Background To conduct a meta-analysis of performance of DNA methylation in women with
high-grade cervical intraepithelial neoplasia (CIN2+). Methods Medline and Embase …
high-grade cervical intraepithelial neoplasia (CIN2+). Methods Medline and Embase …
Triage by methylation-marker testing versus cytology in women who test HPV-positive on self-collected cervicovaginal specimens (PROHTECT-3): a randomised …
VMJ Verhoef, RP Bosgraaf, FJ van Kemenade… - The lancet …, 2014 - thelancet.com
Background Cytology is a widely used method of triaging women who test positive for
human papillomavirus (HPV). However, self-sampled specimens, which can substantially …
human papillomavirus (HPV). However, self-sampled specimens, which can substantially …
[HTML][HTML] Virtues and weaknesses of DNA methylation as a test for cervical cancer prevention
Epigenetics is the study of heritable and non-heritable genetic coding that is additive to
information contained within classical DNA base pair sequences. Differential methylation …
information contained within classical DNA base pair sequences. Differential methylation …
Human papillomavirus and cervical cancer: biomarkers for improved prevention efforts
While organized screening programs in industrialized countries have significantly reduced
cervical cancer incidence, cytology-based screening has several limitations. Equivocal or …
cervical cancer incidence, cytology-based screening has several limitations. Equivocal or …
New technologies and procedures for cervical cancer screening
The clearly higher sensitivity and reproducibility of human papillomavirus (HPV) DNA testing
for high-grade cervical intraepithelial neoplasia (CIN) has led to widespread calls to …
for high-grade cervical intraepithelial neoplasia (CIN) has led to widespread calls to …
Predicting hub genes associated with cervical cancer through gene co-expression networks
Cervical cancer is the third most common malignancy in women worldwide. It remains a
leading cause of cancer-related death for women in develo** countries. In order to …
leading cause of cancer-related death for women in develo** countries. In order to …