High‐throughput DNA sequencing–concepts and limitations
Recent advances in DNA sequencing have revolutionized the field of genomics, making it
possible for even single research groups to generate large amounts of sequence data very …
possible for even single research groups to generate large amounts of sequence data very …
The future of ancient DNA: technical advances and conceptual shifts
Technological innovations such as next generation sequencing and DNA hybridisation
enrichment have resulted in multi‐fold increases in both the quantity of ancient DNA …
enrichment have resulted in multi‐fold increases in both the quantity of ancient DNA …
A draft sequence of the Neandertal genome
Neandertals, the closest evolutionary relatives of present-day humans, lived in large parts of
Europe and western Asia before disappearing 30,000 years ago. We present a draft …
Europe and western Asia before disappearing 30,000 years ago. We present a draft …
Single‐tube library preparation for degraded DNA
C Carøe, S Gopalakrishnan, L Vinner… - Methods in Ecology …, 2018 - Wiley Online Library
In recent years, massive parallel sequencing has revolutionised the study of degraded DNA,
thus enabling the field of ancient DNA to evolve into that of paleogenomics. Despite these …
thus enabling the field of ancient DNA to evolve into that of paleogenomics. Despite these …
Methods and systems for processing polynucleotides
B Hindson, C Hindson, M Schnall-Levin… - US Patent …, 2019 - Google Patents
Provisional application No. 61/737, 374, filed on Dec. 14, 2012, provisional application No.
61/844, 804, filed on Jul. 10, 2013, provisional application No. 61/840, 403, filed on Jun. 27 …
61/844, 804, filed on Jul. 10, 2013, provisional application No. 61/840, 403, filed on Jun. 27 …
Single-stranded DNA library preparation from highly degraded DNA using T4 DNA ligase
MT Gansauge, T Gerber, I Glocke… - Nucleic acids …, 2017 - academic.oup.com
DNA library preparation for high-throughput sequencing of genomic DNA usually involves
ligation of adapters to double-stranded DNA fragments. However, for highly degraded DNA …
ligation of adapters to double-stranded DNA fragments. However, for highly degraded DNA …
Removal of deaminated cytosines and detection of in vivo methylation in ancient DNA
ABSTRACT DNA sequences determined from ancient organisms have high error rates,
primarily due to uracil bases created by cytosine deamination. We use synthetic …
primarily due to uracil bases created by cytosine deamination. We use synthetic …
Methods and systems for droplet-based single cell barcoding
K Belhocine, R Bharadwaj, C Hindson… - US Patent …, 2019 - Google Patents
US10428326B2 - Methods and systems for droplet-based single cell barcoding - Google
Patents US10428326B2 - Methods and systems for droplet-based single cell barcoding …
Patents US10428326B2 - Methods and systems for droplet-based single cell barcoding …
Compositions and methods for sample processing
B Hindson, C Hindson, M Schnall-Levin… - US Patent …, 2019 - Google Patents
2014-09-25 Assigned to 10X TECHNOLOGIES, INC. reassignment 10X TECHNOLOGIES,
INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS) …
INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS) …
Methods and systems for processing polynucleotides
P Belgrader, Z Bent, TS Mikkelsen, P Ryvkin… - US Patent …, 2019 - Google Patents
US10323278B2 - Methods and systems for processing polynucleotides - Google Patents
US10323278B2 - Methods and systems for processing polynucleotides - Google Patents …
US10323278B2 - Methods and systems for processing polynucleotides - Google Patents …