Among the physicochemical cues in the cellular microenvironment that orchestrate cell
processes, the different levels of curvature in the extracellular matrix and intrinsic to the …

Mathematical models are indispensable for disentangling the interactions through which
biological components work together to generate the forces and flows that position, mix, and …

The multicellular organization of diverse systems, including embryos, intestines, and tumors
relies on coordinated cell migration in curved environments. In these settings, cells establish …

Soft materials are usually defined as materials made of mesoscopic entities, often self-
organised, sensitive to thermal fluctuations and to weak perturbations. Archetypal examples …

Large cells often rely on cytoplasmic flows for intracellular transport, maintaining
homeostasis, and positioning cellular components. Understanding the mechanisms of these …

Morphodynamic equations governing the behaviour of active nematic fluids on deformable
curved surfaces are constructed in the large deformation limit. Emphasis is placed on the …

Orientational order is a common feature of many biological and synthetic materials.
Topological defects are discontinuities in this order that are often coupled to geometric …

Embryos develop in a surrounding that guides key aspects of their development. For
example, the anteroposterior (AP) body axis is always aligned with the geometric long axis …

Coordinated cellular movements are key processes in tissue morphogenesis. Using a cell-
based modeling approach we study the dynamics of epithelial layers lining surfaces with …

Recent advances in cell biology and experimental techniques using reconstituted cell
extracts have generated significant interest in understanding how geometry and topology …