Effects of mesenchymal stem cell-derived exosomes on autoimmune diseases

Z Shen, W Huang, J Liu, J Tian, S Wang… - Frontiers in …, 2021 - frontiersin.org
Recent years, the immunosuppressive properties of mesenchymal stem cells (MSCs) have
been demonstrated in preclinical studies and trials of inflammatory and autoimmune …

Diabetes and sarcopenic obesity: pathogenesis, diagnosis, and treatments

M Wang, Y Tan, Y Shi, X Wang, Z Liao… - Frontiers in …, 2020 - frontiersin.org
Sarcopenic obesity and diabetes are two increasing health problems worldwide, which both
share many common risk factors, such as aging, and general obesity. The pathogenesis of …

Biogenesis, composition and potential therapeutic applications of mesenchymal stem cells derived exosomes in various diseases

YG Yuan, JL Wang, YX Zhang, L Li… - International Journal …, 2023 - Taylor & Francis
Exosomes are nanovesicles with a wide range of chemical compositions used in many
different applications. Mesenchymal stem cell-derived exosomes (MSCs-EXOs) are …

Treatment strategies against diabetes: Success so far and challenges ahead

R Khursheed, SK Singh, S Wadhwa, B Kapoor… - European journal of …, 2019 - Elsevier
The growing disease burden of diabetes mellitus is an important public health concern,
affecting over 400 million people globally. This epidemic, if not controlled in time, leads to …

Diabetic muscular atrophy: molecular mechanisms and promising therapies

Y Shen, M Li, K Wang, G Qi, H Liu, W Wang… - Frontiers in …, 2022 - frontiersin.org
Diabetes mellitus (DM) is a typical chronic disease that can be divided into 2 types,
dependent on insulin deficiency or insulin resistance. Incidences of diabetic complications …

Wound healing potential of insulin-loaded nanoemulsion with Aloe vera gel in diabetic rats

T Chakraborty, S Gupta, A Nair, S Chauhan… - Journal of Drug Delivery …, 2021 - Elsevier
Diabetes skin infection is a very common disorder in hyperglycemic patients. This study
evaluated the prospective of develo** a topical gel formulation of Aloe vera with insulin …

Mechanisms of Antidiabetic Activity of Methanolic Extract of Punica granatum Leaves in Nicotinamide/Streptozotocin-Induced Type 2 Diabetes in Rats

S Pottathil, P Nain, MA Morsy, J Kaur, BE Al-Dhubiab… - Plants, 2020 - mdpi.com
The current study aimed to establish the mechanisms of antidiabetic activity of methanolic
extract of Punica granatum leaves (MEPGL) in nicotinamide/streptozotocin-induced type 2 …

Gut microbiota and type 1 diabetes mellitus: The effect of Mediterranean diet

CM Calabrese, A Valentini, G Calabrese - Frontiers in Nutrition, 2021 - frontiersin.org
Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease resulting from a complex
interplay between genetic susceptibility and environmental factors. Regarding the latter, gut …

Environmental pollution and the risk of develo** metabolic disorders: obesity and diabetes

WJ Khalil, M Akeblersane, AS Khan, ASM Moin… - International Journal of …, 2023 - mdpi.com
To meet the increased need for food and energy because of the economic shift brought
about by the Industrial Revolution in the 19th century, there has been an increase in …

Experimental models to study diabetes mellitus and its complications: limitations and new opportunities

B Martín-Carro, J Donate-Correa… - International Journal of …, 2023 - mdpi.com
Preclinical biomedical models are a fundamental tool to improve the knowledge and
management of diseases, particularly in diabetes mellitus (DM) since, currently, the …