In recent years, a significant breakthrough has emerged in biology, the identification of
lactylation, a novel post‐translational process. This intriguing modification is not limited to a …

Lysine l-lactylation (Kl-la) is a novel protein posttranslational modification (PTM) driven by l-
lactate. This PTM has three isomers: Kl-la, N-ε-(carboxyethyl)-lysine (Kce) and d-lactyl-lysine …

Lactate, a metabolic byproduct, has gained recognition as a highly influential signaling
molecule. Lactylation, an emerging form of post-translational modification derived from …

Intricate coupling between metabolism and protein post-translational modifications (PTMs)
has emerged as a fundamental aspect of cellular regulation. Recent studies demonstrate …

Cell metabolism generates numerous intermediate metabolites that could serve as feedback
and feed-forward regulation substances for posttranslational modification. Lactate, a …

Protein lysine crotonylation has been found to be closely related to the occurrence and
development of various diseases. Currently, site identification of crotonylation is mainly …

Kaposi's sarcoma-associated herpesvirus (KSHV) is a large enveloped, double-stranded
DNA virus that is the causative agent of several types of cancer. KSHV causes persistent …

Over the past decades, nutritional research has undergone a significant shift, moving
beyond merely preventing nutritional deficiencies in populations. Instead, the focus has …

Proteomics explores global-scale protein functions, with post-translational modifications
(PTMs) expanding proteome complexity and functionality. Significant advancements in mass …