TGF-β signaling: from tissue fibrosis to tumor microenvironment
JYF Chung, MKK Chan, JSF Li, ASW Chan… - International Journal of …, 2021 - mdpi.com
Transforming growth factor-β (TGF-β) signaling triggers diverse biological actions in
inflammatory diseases. In tissue fibrosis, it acts as a key pathogenic regulator for promoting …
inflammatory diseases. In tissue fibrosis, it acts as a key pathogenic regulator for promoting …
Oxidative stress as a culprit in diabetic kidney disease
Diabetic kidney disease (DKD) has become the leading cause of end-stage renal disease
(ESRD), and the prevalence of DKD has increased worldwide during recent years. DKD is …
(ESRD), and the prevalence of DKD has increased worldwide during recent years. DKD is …
Identification of key genes in colorectal cancer diagnosis by weighted gene co-expression network analysis
Background The purpose of this study was using bioinformatics tools to identify biomarkers
and molecular factors involved in the diagnosis of colorectal cancer, which are effective for …
and molecular factors involved in the diagnosis of colorectal cancer, which are effective for …
Non-coding RNAs in regulating plaque progression and remodeling of extracellular matrix in atherosclerosis
Non-coding RNAs (ncRNAs) regulate cell proliferation, migration, differentiation,
inflammation, metabolism of clinically important biomolecules, and other cellular processes …
inflammation, metabolism of clinically important biomolecules, and other cellular processes …
Circulating non-coding RNAs in chronic kidney disease and its complications
AJ van Zonneveld, Q Zhao, JI Rotmans… - Nature Reviews …, 2023 - nature.com
Post-transcriptional regulation by non-coding RNAs (ncRNAs) can modulate the expression
of genes involved in kidney physiology and disease. A large variety of ncRNA species exist …
of genes involved in kidney physiology and disease. A large variety of ncRNA species exist …
Deciphering the role of miRNA in reprogramming plant responses to drought stress
Drought is the most prevalent environmental stress that affects plants' growth, development,
and crop productivity. However, plants have evolved adaptive mechanisms to respond to the …
and crop productivity. However, plants have evolved adaptive mechanisms to respond to the …
[HTML][HTML] Identification of urinary extracellular vesicles differentially expressed RNAs in diabetic nephropathy via whole-transcriptome integrated analysis
Z Zhao, Q Yan, L Fang, G Li, Y Liu, J Li, S Pan… - Computers in Biology …, 2023 - Elsevier
Background Diabetic nephropathy (DN) is a common systemic microvascular complication
of diabetes and a leading cause of chronic kidney disease worldwide. Urinary extracellular …
of diabetes and a leading cause of chronic kidney disease worldwide. Urinary extracellular …
Exploring the therapeutic significance of microRNAs and lncRNAs in kidney diseases
LA Bravo-Vázquez, S Paul, MG Colín-Jurado… - Genes, 2024 - mdpi.com
MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are two crucial classes of
transcripts that belong to the major group of non-coding RNAs (ncRNAs). These RNA …
transcripts that belong to the major group of non-coding RNAs (ncRNAs). These RNA …
The regulatory role of miRNA and lncRNA on autophagy in diabetic nephropathy
S Yu, Y Li, X Lu, Z Han, C Li, X Yuan, D Guo - Cellular Signalling, 2024 - Elsevier
Diabetic nephropathy (DN) is a serious complication of diabetes that causes glomerular
sclerosis and end-stage renal disease, leading to ascending morbidity and mortality in …
sclerosis and end-stage renal disease, leading to ascending morbidity and mortality in …
Interactions among long non-coding RNAs and microRNAs influence disease phenotype in diabetes and diabetic kidney disease
Large-scale RNA sequencing and genome-wide profiling data revealed the identification of
a heterogeneous group of noncoding RNAs, known as long noncoding RNAs (lncRNAs) …
a heterogeneous group of noncoding RNAs, known as long noncoding RNAs (lncRNAs) …