TGF-β signaling: from tissue fibrosis to tumor microenvironment

JYF Chung, MKK Chan, JSF Li, ASW Chan… - International Journal of …, 2021 - mdpi.com
Transforming growth factor-β (TGF-β) signaling triggers diverse biological actions in
inflammatory diseases. In tissue fibrosis, it acts as a key pathogenic regulator for promoting …

Oxidative stress as a culprit in diabetic kidney disease

S Su, Z Ma, H Wu, Z Xu, H Yi - Life Sciences, 2023 - Elsevier
Diabetic kidney disease (DKD) has become the leading cause of end-stage renal disease
(ESRD), and the prevalence of DKD has increased worldwide during recent years. DKD is …

Identification of key genes in colorectal cancer diagnosis by weighted gene co-expression network analysis

M Mortezapour, L Tapak, F Bahreini, R Najafi… - Computers in Biology …, 2023 - Elsevier
Background The purpose of this study was using bioinformatics tools to identify biomarkers
and molecular factors involved in the diagnosis of colorectal cancer, which are effective for …

Non-coding RNAs in regulating plaque progression and remodeling of extracellular matrix in atherosclerosis

D Singh, V Rai, DK Agrawal - International Journal of Molecular Sciences, 2022 - mdpi.com
Non-coding RNAs (ncRNAs) regulate cell proliferation, migration, differentiation,
inflammation, metabolism of clinically important biomolecules, and other cellular processes …

Circulating non-coding RNAs in chronic kidney disease and its complications

AJ van Zonneveld, Q Zhao, JI Rotmans… - Nature Reviews …, 2023 - nature.com
Post-transcriptional regulation by non-coding RNAs (ncRNAs) can modulate the expression
of genes involved in kidney physiology and disease. A large variety of ncRNA species exist …

Deciphering the role of miRNA in reprogramming plant responses to drought stress

A Singh, D Jain, J Pandey, M Yadav… - Critical Reviews in …, 2023 - Taylor & Francis
Drought is the most prevalent environmental stress that affects plants' growth, development,
and crop productivity. However, plants have evolved adaptive mechanisms to respond to the …

[HTML][HTML] Identification of urinary extracellular vesicles differentially expressed RNAs in diabetic nephropathy via whole-transcriptome integrated analysis

Z Zhao, Q Yan, L Fang, G Li, Y Liu, J Li, S Pan… - Computers in Biology …, 2023 - Elsevier
Background Diabetic nephropathy (DN) is a common systemic microvascular complication
of diabetes and a leading cause of chronic kidney disease worldwide. Urinary extracellular …

Exploring the therapeutic significance of microRNAs and lncRNAs in kidney diseases

LA Bravo-Vázquez, S Paul, MG Colín-Jurado… - Genes, 2024 - mdpi.com
MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are two crucial classes of
transcripts that belong to the major group of non-coding RNAs (ncRNAs). These RNA …

The regulatory role of miRNA and lncRNA on autophagy in diabetic nephropathy

S Yu, Y Li, X Lu, Z Han, C Li, X Yuan, D Guo - Cellular Signalling, 2024 - Elsevier
Diabetic nephropathy (DN) is a serious complication of diabetes that causes glomerular
sclerosis and end-stage renal disease, leading to ascending morbidity and mortality in …

Interactions among long non-coding RNAs and microRNAs influence disease phenotype in diabetes and diabetic kidney disease

SP Srivastava, JE Goodwin, P Tripathi… - International Journal of …, 2021 - mdpi.com
Large-scale RNA sequencing and genome-wide profiling data revealed the identification of
a heterogeneous group of noncoding RNAs, known as long noncoding RNAs (lncRNAs) …