Cardiovascular disease (CVD) is a key cause of deaths worldwide, comprising 15–17% of
healthcare expenditure in developed countries. Current records estimate an annual global …

Skeletal muscle is a metabolically active tissue and the major body protein reservoir. Drop in
ambient oxygen pressure likely results in a decrease in muscle cells oxygenation, reactive …

Inorganic nitrate was once considered an oxidation end product of nitric oxide metabolism
with little biological activity. However, recent studies have demonstrated that dietary nitrate …

Probiotics play a crucial role in largemouth bass aquaculture, primarily in enhancing water
quality, preventing fish diseases, promoting largemouth bass growth, and boosting immunity …

Skeletal muscle undergoes metabolic remodelling in response to environmental hypoxia,
yet aspects of this process remain controversial. Broadly, environmental hypoxia has been …

The response to insufficient oxygen (hypoxia) is orchestrated by the conserved hypoxia-
inducible factor (HIF). However, HIF-independent hypoxia response pathways exist that act …

Myocardial regeneration capacity declines during the first week after birth, and this decline is
linked to adaptation to oxidative metabolism. Utilizing this regenerative window, we …

Cardiac metabolism represents a crucial and essential connecting bridge between the
healthy and diseased heart. The cardiac muscle, which may be considered an omnivore …

High-altitude environments require that animals meet the metabolic O2 demands for
locomotion and thermogenesis in O2-thin air, but the degree to which convergent metabolic …

Background Skeletal muscle atrophy is a common feature of numerous chronic pathologies
and is correlated with patient mortality. The REDD1 protein is currently recognized as a …