Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

More than four decades have passed since the first example of a light-activated (caged)
compound was described. In the intervening years, a large number of light-responsive …

Light is a particularly appealing tool for on‐demand drug delivery due to its noninvasive
nature, ease of application, and exquisite temporal and spatial control. Great progress is …

Therapeutic systems with site‐specific pharmaceutical activation hold great promise to
enhance therapeutic efficacy while reducing systemic toxicity in cancer therapy. With …

Light-based therapeutic and imaging modalities, which emerge in clinical applications, rely
on molecular tools, such as photocleavable protecting groups and photoswitches that …

Biological signalling is regulated through a complex and tightly choreographed interplay
between cells and their extracellular matrix. The spatiotemporal control of these interactions …

Nanotechnology has begun to play a remarkable role in various fields of science and
technology. In biomedical applications, nanoparticles have opened new horizons, especially …

Recent protocols and reactions for catalytic radical perfluoroalkylations will be described.
The production of perfluoroalkyl radicals (RF= C n F2 n+ 1, n≥ 2), which effect both addition …

Red light has the advantages of low energy, less health risks, and high penetration depth
through various media. Herein, a helical carbenium ion (N, N′-di-n-propyl-1, 13 …

Photopharmacological tools enable the precise spatiotemporal control of small molecule
drugs. Amongst them, caged compounds incorporate a photolabile moiety which is released …