Overview of the mechanisms that may contribute to the non-redundant activities of interferon-inducible CXC chemokine receptor 3 ligands

M Metzemaekers, V Vanheule, R Janssens… - Frontiers in …, 2018 - frontiersin.org
The inflammatory chemokines CXCL9, CXCL10, and CXCL11 are predominantly induced
by interferon (IFN)-γ and share an exclusive chemokine receptor named CXC chemokine …

Astrocyte and oligodendrocyte cross-talk in the central nervous system

E Nutma, D van Gent, S Amor, LAN Peferoen - Cells, 2020 - mdpi.com
Over the last decade knowledge of the role of astrocytes in central nervous system (CNS)
neuroinflammatory diseases has changed dramatically. Rather than playing a merely …

Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases

L Cartier, O Hartley, M Dubois-Dauphin… - Brain Research …, 2005 - Elsevier
Chemokines were originally described as chemotactic cytokines involved in leukocyte
trafficking. Research over the last decade, however, has shown that chemokine receptors …

CXC chemokines: the regulatory link between inflammation and angiogenesis

P Romagnani, L Lasagni, F Annunziato, M Serio… - Trends in …, 2004 - cell.com
Chemokines are multifunctional mediators mainly responsible for leukocyte recruitment to
inflamed tissues. Cytokines of the CXC family, however, also have a pivotal role in the …

HIV and co‐infections

CC Chang, M Crane, JL Zhou, M Mina… - Immunological …, 2013 - Wiley Online Library
Despite significant reductions in morbidity and mortality secondary to availability of effective
combination anti‐retroviral therapy (cART), human immunodeficiency virus (HIV) infection …

Chemokines: a new class of neuromodulator?

W Rostène, P Kitabgi, SM Parsadaniantz - Nature Reviews …, 2007 - nature.com
Chemokines are not only found in the immune system or expressed in inflammatory
conditions: they are constitutively present in the brain in both glial cells and neurons …

Role of chemokines in angiogenesis: CXCL12/SDF-1 and CXCR4 interaction, a key regulator of endothelial cell responses

R Salcedo, JJ Oppenheim - Microcirculation, 2003 - Taylor & Francis
Chemokines are small proteins that act as cell attractants via the activation of G protein-
coupled receptors. Chemokines play an important role in several pathophysiological …

Regulation of pulmonary fibrosis by chemokine receptor CXCR3

D Jiang, J Liang, J Hodge, B Lu, Z Zhu, S Yu… - The Journal of clinical …, 2004 - jci.org
CXC chemokine receptor 3 (CXCR3) is the receptor for the IFN-γ–inducible CXC
chemokines MIG/CXCL9, IP-10/CXCL10, and I-TAC/CXCL11. CXCR3 is expressed on …

Characterization of chemokines and their receptors in the central nervous system: physiopathological implications

A Bajetto, R Bonavia, S Barbero… - Journal of …, 2002 - Wiley Online Library
Chemokines represent key factors in the outburst of the immune response, by activating and
directing the leukocyte traffic, both in lymphopoiesis and in immune surveillance …

Role of chemokines in endocrine autoimmune diseases

M Rotondi, L Chiovato, S Romagnani, M Serio… - Endocrine …, 2007 - academic.oup.com
Chemokines are a group of peptides of low molecular weight that induce the chemotaxis of
different leukocyte subtypes. The major function of chemokines is the recruitment of …