Statistical challenges in longitudinal microbiome data analysis

S Kodikara, S Ellul, KA Lê Cao - Briefings in Bioinformatics, 2022 - academic.oup.com
The microbiome is a complex and dynamic community of microorganisms that co-exist
interdependently within an ecosystem, and interact with its host or environment. Longitudinal …

Cohesion: a method for quantifying the connectivity of microbial communities

CM Herren, KD McMahon - The ISME Journal, 2017 - academic.oup.com
The ability to predict microbial community dynamics lags behind the quantity of data
available in these systems. Most predictive models use only environmental parameters …

Ecosystem-specific microbiota and microbiome databases in the era of big data

V Lobanov, A Gobet, A Joyce - Environmental Microbiome, 2022 - Springer
The rapid development of sequencing methods over the past decades has accelerated both
the potential scope and depth of microbiota and microbiome studies. Recent developments …

Microdiversity ensures the maintenance of functional microbial communities under changing environmental conditions

N García-García, J Tamames, AM Linz… - The ISME …, 2019 - academic.oup.com
Microdiversity can lead to different ecotypes within the same species. These are assumed to
provide stability in time and space to those species. However, the role of microdiversity in …

Species invasions shift microbial phenology in a two-decade freshwater time series

RR Rohwer, RJ Hale… - Proceedings of the …, 2023 - National Acad Sciences
Invasive species impart abrupt changes on ecosystems, but their impacts on microbial
communities are often overlooked. We paired a 20 y freshwater microbial community time …

TaxAss: leveraging a custom freshwater database achieves fine-scale taxonomic resolution

RR Rohwer, JJ Hamilton, RJ Newton, KD McMahon - Msphere, 2018 - Am Soc Microbiol
Taxonomy assignment of freshwater microbial communities is limited by the minimally
curated phylogenies used for large taxonomy databases. Here we introduce TaxAss, a …

Freshwater carbon and nutrient cycles revealed through reconstructed population genomes

AM Linz, S He, SLR Stevens, K Anantharaman… - PeerJ, 2018 - peerj.com
Although microbes mediate much of the biogeochemical cycling in freshwater, the
categories of carbon and nutrients currently used in models of freshwater biogeochemical …

acI Actinobacteria assemble a functional actinorhodopsin with natively synthesized retinal

JR Dwulit-Smith, JJ Hamilton… - Applied and …, 2018 - Am Soc Microbiol
Freshwater lakes harbor complex microbial communities, but these ecosystems are often
dominated by acI Actinobacteria. Members of this cosmopolitan lineage are proposed to …

Robust and automatic definition of microbiome states

B García-Jiménez, MD Wilkinson - PeerJ, 2019 - peerj.com
Analysis of microbiome dynamics would allow elucidation of patterns within microbial
community evolution under a variety of biologically or economically important …

[PDF][PDF] A two-decade microbial time series from a freshwater lake, introducing the limony and TYMEFLIES datasets

RR Rohwer, KD McMahon - bioRxiv, 2022 - scholar.archive.org
Lakes are focal points of biogeochemical cycling on the terrestrial landscape, and microbial
13 communities are the machines driving these processes. However, our view into how 14 …