Protective effect of curcumin against heavy metals-induced liver damage

WR García-Niño, J Pedraza-Chaverrí - Food and chemical toxicology, 2014‏ - Elsevier
Occupational or environmental exposures to heavy metals produce several adverse health
effects. The common mechanism determining their toxicity and carcinogenicity is the …

[HTML][HTML] Mitochondria in neuroprotection by phytochemicals: Bioactive polyphenols modulate mitochondrial apoptosis system, function and structure

M Naoi, Y Wu, M Shamoto-Nagai… - International journal of …, 2019‏ - mdpi.com
In aging and neurodegenerative diseases, loss of distinct type of neurons characterizes
disease-specific pathological and clinical features, and mitochondria play a pivotal role in …

Cardamonin inhibits breast cancer growth by repressing HIF-1α-dependent metabolic reprogramming

J **, S Qiu, P Wang, X Liang, F Huang, H Wu… - Journal of Experimental …, 2019‏ - Springer
Background Cardamonin, a chalcone isolated from Alpiniae katsumadai, has anti-
inflammatory and anti-tumor activities. However, the molecular mechanism by which …

Carbon dots prepared from ginger exhibiting efficient inhibition of human hepatocellular carcinoma cells

CL Li, CM Ou, CC Huang, WC Wu, YP Chen… - Journal of Materials …, 2014‏ - pubs.rsc.org
Fluorescent carbon nanodots (C-dots; 4.3±0.8 nm) from fresh tender ginger juice provide
high suppression of the growth of human hepatocellular carcinoma cells (HepG2), with low …

[HTML][HTML] Anti-cancer agents in proliferation and cell death: the calcium connection

E Varghese, SM Samuel, Z Sadiq, P Kubatka… - International journal of …, 2019‏ - mdpi.com
Calcium (Ca2+) signaling and the modulation of intracellular calcium ([Ca2+] i) levels play
critical roles in several key processes that regulate cellular survival, growth, differentiation …

A functionalized octahedral palladium nanozyme as a radical scavenger for ameliorating Alzheimer's disease

Z Jia, X Yuan, J Wei, X Guo, Y Gong, J Li… - … applied materials & …, 2021‏ - ACS Publications
Oxidative stress is always mentioned as a pathologic appearance of Alzheimer's disease
(AD). It is attributed to mitochondrial dysfunction closely linked to Aβ deposition and …

Multifunctional curcumin-loaded mesoporous silica nanoparticles for cancer chemoprevention and therapy

NS Elbialy, SF Aboushoushah, BF Sofi… - … and Mesoporous Materials, 2020‏ - Elsevier
This study aims to synthesize smart mesoporous silica nanocarrier for curcumin (Cur) as a
nutraceutical anticancer agent. Multifunctional PEG-MSNPs-Cur were synthesized to …

Curcumin induces crosstalk between autophagy and apoptosis mediated by calcium release from the endoplasmic reticulum, lysosomal destabilization and …

A Moustapha, PA Pérétout, NE Rainey, F Sureau… - Cell Death …, 2015‏ - nature.com
Curcumin, a major active component of turmeric (Curcuma longa, L.), has anticancer effects.
In vitro studies suggest that curcumin inhibits cancer cell growth by activating apoptosis, but …

Cerium oxide nanoparticle modified scaffold interface enhances vascularization of bone grafts by activating calcium channel of mesenchymal stem cells

J **ang, J Li, J He, X Tang, C Dou, Z Cao… - … applied materials & …, 2016‏ - ACS Publications
Insufficient blood perfusion is one of the critical problems that hamper the clinical application
of tissue engineering bone (TEB). Current methods for improving blood vessel distribution in …

OPFRs and BFRs induced A549 cell apoptosis by caspase-dependent mitochondrial pathway

X Yu, H Yin, H Peng, G Lu, Z Liu, Z Dang - Chemosphere, 2019‏ - Elsevier
Organophosphate flame retardants (OPFRs) and brominated flame retardants (BFRs) are
frequently detected in indoor environment at high levels, posing health risks to humans …