A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia

AJ McGuinness, JA Davis, SL Dawson… - Molecular …, 2022 - nature.com
The emerging understanding of gut microbiota as 'metabolic machinery'influencing many
aspects of physiology has gained substantial attention in the field of psychiatry. This is …

[HTML][HTML] Brain–gut–microbiota axis in depression: A historical overview and future directions

L Chang, Y Wei, K Hashimoto - Brain Research Bulletin, 2022 - Elsevier
Depression is the most common mental disorder and a leading cause of disability
worldwide. Despite abundant research, the precise mechanisms underlying the …

Immunoregulatory role of the gut microbiota in inflammatory depression

P Liu, Z Liu, J Wang, J Wang, M Gao, Y Zhang… - Nature …, 2024 - nature.com
Inflammatory depression is a treatment-resistant subtype of depression. A causal role of the
gut microbiota as a source of low-grade inflammation remains unclear. Here, as part of an …

Perturbations in gut microbiota composition in psychiatric disorders: a review and meta-analysis

VL Nikolova, MRB Smith, LJ Hall, AJ Cleare… - JAMA …, 2021 - jamanetwork.com
Importance Evidence of gut microbiota perturbations has accumulated for multiple
psychiatric disorders, with microbiota signatures proposed as potential biomarkers …

Gut microbiome-wide association study of depressive symptoms

D Radjabzadeh, JA Bosch, AG Uitterlinden… - Nature …, 2022 - nature.com
Depression is one of the most poorly understood diseases due to its elusive pathogenesis.
There is an urgency to identify molecular and biological mechanisms underlying depression …

The gut microbiome in depression and potential benefit of prebiotics, probiotics and synbiotics: a systematic review of clinical trials and observational studies

SR Alli, I Gorbovskaya, JCW Liu, NJ Kolla… - International journal of …, 2022 - mdpi.com
An emerging body of literature demonstrates differences in the gut microbiome (GMB) of
patients with major depressive disorder (MDD) compared to healthy controls (HC), as well …

Toward a deeper understanding of gut microbiome in depression: the promise of clinical applicability

L Liu, H Wang, H Zhang, X Chen, Y Zhang… - Advanced …, 2022 - Wiley Online Library
The emergence of the coronavirus disease 2019 pandemic has dramatically increased the
global prevalence of depression. Unfortunately, antidepressant drugs benefit only a small …

Gut microbiota in anxiety and depression: unveiling the relationships and management options

A Kumar, J Pramanik, N Goyal, D Chauhan… - Pharmaceuticals, 2023 - mdpi.com
The gut microbiota is critical for maintaining human health and the immunological system.
Several neuroscientific studies have shown the significance of microbiota in develo** …

Vagus nerve and underlying impact on the gut microbiota-brain axis in behavior and neurodegenerative diseases

Y Han, B Wang, H Gao, C He, R Hua… - Journal of …, 2022 - Taylor & Francis
The gut microbiota is the most abundant and diverse microbiota in the human body and the
vagus nerve is the most widely distributed and complex nerve in the body, both of them are …

Mechanistic insights into the link between gut dysbiosis and major depression: an extensive review

S Sonali, B Ray, H Ahmed Tousif, AG Rathipriya… - Cells, 2022 - mdpi.com
Depression is a highly common mental disorder, which is often multifactorial with sex,
genetic, environmental, and/or psychological causes. Recent advancements in biomedical …