Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions
C Qin, S Yang, YH Chu, H Zhang, XW Pang… - Signal transduction and …, 2022 - nature.com
Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …
severe neural injuries, and is one of the leading causes of death and disability worldwide …
Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications
Ischemic stroke caused by arterial occlusion is the most common type of stroke, which is
among the most frequent causes of disability and death worldwide. Current treatment …
among the most frequent causes of disability and death worldwide. Current treatment …
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …
Since then, this topic has received increasing attention, and many scientists have entered …
Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles
Autophagy is central to the maintenance of organismal homeostasis in both physiological
and pathological situations. Accordingly, alterations in autophagy have been linked to …
and pathological situations. Accordingly, alterations in autophagy have been linked to …
Empagliflozin Attenuates Non-Alcoholic Fatty Liver Disease (NAFLD) in High Fat Diet Fed ApoE(-/-) Mice by Activating Autophagy and Reducing ER Stress and …
N Nasiri-Ansari, C Nikolopoulou, K Papoutsi… - International journal of …, 2021 - mdpi.com
Aims/hypothesis: SGLT-2 inhibitors (SGLT-2i) have been studied as potential treatments
against NAFLD, showing varying beneficial effects. The molecular mechanisms mediating …
against NAFLD, showing varying beneficial effects. The molecular mechanisms mediating …
Roles of autophagy in oxidative stress
HR Yun, YH Jo, J Kim, Y Shin, SS Kim… - International journal of …, 2020 - mdpi.com
Autophagy is a catabolic process for unnecessary or dysfunctional cytoplasmic contents by
lysosomal degradation pathways. Autophagy is implicated in various biological processes …
lysosomal degradation pathways. Autophagy is implicated in various biological processes …
Autophagy in ischemic stroke
Autophagy is a self-eating cellular catabolic pathway, through which long-lived proteins,
damaged organelles and misfolded proteins are degraded and recycled for the …
damaged organelles and misfolded proteins are degraded and recycled for the …
[HTML][HTML] Melatonin as a master regulator of cell death and inflammation: molecular mechanisms and clinical implications for newborn care
Melatonin, more commonly known as the sleep hormone, is mainly secreted by the pineal
gland in dark conditions and regulates the circadian rhythm of the organism. Its intrinsic …
gland in dark conditions and regulates the circadian rhythm of the organism. Its intrinsic …
Cell death mechanisms in stroke and novel molecular and cellular treatment options
E Sekerdag, I Solaroglu… - Current …, 2018 - ingentaconnect.com
As a result of ischemia or hemorrhage, blood supply to neurons is disrupted which
subsequently promotes a cascade of pathophysiological responses resulting in cell loss …
subsequently promotes a cascade of pathophysiological responses resulting in cell loss …
Neonatal hypoxia ischaemia: mechanisms, models, and therapeutic challenges
Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …
human neonates, and is often associated with persistent motor, sensory, and cognitive …