Advanced cell culture techniques for cancer drug discovery

CJ Lovitt, TB Shelper, VM Avery - Biology, 2014 - mdpi.com
Human cancer cell lines are an integral part of drug discovery practices. However, modeling
the complexity of cancer utilizing these cell lines on standard plastic substrata, does not …

Applying evolutionary biology to address global challenges

SP Carroll, PS Jørgensen, MT Kinnison, CT Bergstrom… - science, 2014 - science.org
BACKGROUND Differences among species in their ability to adapt to environmental change
threaten biodiversity, human health, food security, and natural resource availability …

The central importance of ecological spatial connectivity to effective coastal marine protected areas and to meeting the challenges of climate change in the marine …

MH Carr, SP Robinson, C Wahle… - Aquatic …, 2017 - Wiley Online Library
The several forms of ecological spatial connectivity–population, genetic, community,
ecosystem–are among the most important ecological processes in determining the …

Ecosystem-based fisheries management requires a change to the selective fishing philosophy

S Zhou, ADM Smith, AE Punt… - Proceedings of the …, 2010 - National Acad Sciences
Globally, many fish species are overexploited, and many stocks have collapsed. This crisis,
along with increasing concerns over flow-on effects on ecosystems, has caused a …

SYNTHESIS: life history change in commercially exploited fish stocks: an analysis of trends across studies

DMT Sharpe, AP Hendry - Evolutionary applications, 2009 - Wiley Online Library
Age and size at maturation have declined dramatically in many commercial fish stocks over
the past few decades–changes that have been widely attributed to fishing pressure. We …

Implications of fisheries‐induced evolution for stock rebuilding and recovery

K Enberg, C Jørgensen, ES Dunlop… - Evolutionary …, 2009 - Wiley Online Library
Worldwide depletion of fish stocks has led fisheries managers to become increasingly
concerned about rebuilding and recovery planning. To succeed, factors affecting recovery …

Spawning period of Mediterranean marine fishes

AC Tsikliras, E Antonopoulou, KI Stergiou - Reviews in Fish Biology and …, 2010 - Springer
We collected all available information (ie international and local journals, conference
proceedings, theses, technical reports) on the spawning season (n= 511 stocks, 168 …

Eco‐genetic modeling of contemporary life‐history evolution

ES Dunlop, M Heino, U Dieckmann - Ecological Applications, 2009 - Wiley Online Library
We present eco‐genetic modeling as a flexible tool for exploring the course and rates of
multi‐trait life‐history evolution in natural populations. We build on existing modeling …

Evolutionary impact assessment: accounting for evolutionary consequences of fishing in an ecosystem approach to fisheries management

AT Laugen, GH Engelhard, R Whitlock… - Fish and …, 2014 - Wiley Online Library
Managing fisheries resources to maintain healthy ecosystems is one of the main goals of the
ecosystem approach to fisheries (EAF). While a number of international treaties call for the …

Predictive systems ecology

MR Evans, M Bithell, SJ Cornell… - … of the Royal …, 2013 - royalsocietypublishing.org
Human societies, and their well-being, depend to a significant extent on the state of the
ecosystems that surround them. These ecosystems are changing rapidly usually in response …