Thermosensitive hydrogel releasing nitric oxide donor and anti-CTLA-4 micelles for anti-tumor immunotherapy

J Kim, DM Francis, LF Sestito, PA Archer… - Nature …, 2022 - nature.com
Due to their autosynchronous roles in sha** the anti-tumor immune response, complex
immune regulatory networks acting both locally within the tumor microenvironment as well …

Mechano-responsive, tough, and antibacterial zwitterionic hydrogels with controllable drug release for wound healing applications

K Fang, R Wang, H Zhang, L Zhou, T Xu… - … Applied Materials & …, 2020 - ACS Publications
Acute wounds subject to frequent deformations are difficult to be treated because the
healing process was easily interfered by external mechanical forces. Traditional wound …

[HTML][HTML] Formation and stabilization of gold nanoparticles in bovine serum albumin solution

I Matei, CM Buta, IM Turcu, D Culita, C Munteanu… - Molecules, 2019 - mdpi.com
The formation and growth of gold nanoparticles (AuNPs) were investigated in pH 7 buffer
solution of bovine serum albumin (BSA) at room temperature. The processes were …

Nano Differential Scanning Fluorimetry as a Rapid Stability Assessment Tool in the Nanoformulation of Proteins

S Lisina, W Inam, M Huhtala, F Howaili, H Zhang… - Pharmaceutics, 2023 - mdpi.com
The development and production of innovative protein-based therapeutics is a complex and
challenging avenue. External conditions such as buffers, solvents, pH, salts, polymers …

Complex interaction of caffeic acid with bovine serum albumin: calorimetric, spectroscopic and molecular docking evidence

A Precupas, R Sandu, AR Leonties… - New Journal of …, 2017 - pubs.rsc.org
Herein, the interaction between caffeic acid (CA), a hydroxycinnamic acid with favorable
health impacts through the prevention of degenerative pathologies, and bovine serum …

Gallic acid influence on bovine serum albumin thermal stability

A Precupas, AR Leonties, A Neacsu, R Sandu… - New Journal of …, 2019 - pubs.rsc.org
Gallic acid (GA) is a naturally occurring plant phenolic acid with moderate affinity for BSA,
but its presence in different concentrations may change the thermal stability of the protein …

In situ nanotransformable hydrogel for chemo-photothermal therapy of localized tumors and targeted therapy of highly metastatic tumors

S Baseeruddin Alvi, R PS, N Begum… - … Applied Materials & …, 2021 - ACS Publications
Metastasis is one of the predisposing factors for cancer-related mortalities worldwide.
Patients with advanced cancers (stage IV) receive palliative care with minimal possibility of …

Calorimetric, spectroscopic and computational investigation of morin binding effect on bovine serum albumin stability

A Precupas, R Sandu, AVF Neculae, A Neacsu… - Journal of Molecular …, 2021 - Elsevier
The interaction of morin (Mor) with bovine serum albumin (BSA) was investigated using
calorimetric, spectroscopic and computational methods. The ligand binding to protein has …

Development of Pluronic® nanocarriers comprising pheophorbide, Zn-pheophorbide, lapachol and β-lapachone combined drugs: photophysical and spectroscopic …

K da SS Campanholi, AP Gerola, BH Vilsinski… - Dyes and …, 2018 - Elsevier
Therapy efficiency is ruled by a single agent, which can be enhanced using an adjuvant,
increasing cell inhibition in a synergetic aspect. Taking this into account, the …

Triblock-copolymer-assisted mixed-micelle formation results in the refolding of unfolded protein

R Mondal, N Ghosh, BK Paul, S Mukherjee - Langmuir, 2018 - ACS Publications
The present work reports a new strategy for triblock-copolymer-assisted refolding of sodium
dodecyl sulfate (SDS)-induced unfolded serum protein human serum albumin (HSA) by …