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Unveiling promising breast cancer biomarkers: An integrative approach combining bioinformatics analysis and experimental verification
Background Breast cancer remains a significant health challenge worldwide, necessitating
the identification of reliable biomarkers for early detection, accurate prognosis, and targeted …
the identification of reliable biomarkers for early detection, accurate prognosis, and targeted …
Cell-of-origin targeted drug repurposing for triple-negative and inflammatory breast carcinoma with HDAC and HSP90 inhibitors combined with niclosamide
Simple Summary The human body is composed of hundreds of different normal cell types.
Some of the important and unique features of these normal cell types are inherited by the …
Some of the important and unique features of these normal cell types are inherited by the …
Nucleosome reorganisation in breast cancer tissues
Background Nucleosome repositioning in cancer is believed to cause many changes in
genome organisation and gene expression. Understanding these changes is important to …
genome organisation and gene expression. Understanding these changes is important to …
The transcription factor ZNF92 suppresses CD8 (+) T cell viability and promotes malignant progression in lung adenocarcinoma by elevating PD-L1 expression
X Liu, J Liu, W Wan, L Guo, J Zhang - Molecular & Cellular Toxicology, 2025 - Springer
Background In the tumor microenvironment (TME), exhausted CD8 (+) T cells exhibit the
impaired cytotoxic ability and function as the predominant responder to immune checkpoint …
impaired cytotoxic ability and function as the predominant responder to immune checkpoint …