Large-vessel vasculitis (LVV) manifests as inflammation of the aorta and its major branches
and is the most common primary vasculitis in adults. LVV comprises two distinct conditions …

Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are closely related conditions
characterized by systemic inflammation, a predominant IL-6 signature, an excellent …

Objective To develop recommendations for cardiovascular risk (CVR) management in gout,
vasculitis, systemic sclerosis (SSc), myositis, mixed connective tissue disease (MCTD) …

Objectives To update the EULAR recommendations for the use of imaging modalities in
primary large vessel vasculitis (LVV). Methods A systematic literature review update was …

Abstract Objective The European Society for Vascular Surgery (ESVS) has developed
clinical practice guidelines for the care of patients with aneurysms of the abdominal aorta …

Objectives Granulocyte-macrophage colony-stimulating factor (GM-CSF) is implicated in
pathogenesis of giant cell arteritis. We evaluated the efficacy of the GM-CSF receptor …

Objectives To develop treat-to-target (T2T) recommendations in giant cell arteritis (GCA) and
polymyalgia rheumatica (PMR). Methods A systematic literature review was conducted to …

Background The treatment of giant cell arteritis with glucocorticoid-sparing agents is an
unmet medical need. We evaluated the efficacy and safety of secukinumab, an anti …

Background/purpose Preclinical vascular inflammation models have demonstrated effective
suppression of arterial wall lesional T cells through inhibition of Janus kinase 3 and JAK1 …

Giant cell arteritis (GCA), the most common primary vasculitis in adults, is a granulomatous
systemic vasculitis usually affecting the aorta and its major branches, particularly the carotid …