Integration of molecular docking analysis and molecular dynamics simulations for studying food proteins and bioactive peptides

A Vidal-Limon, JE Aguilar-Toalá… - Journal of agricultural …, 2022 - ACS Publications
In silico tools, such as molecular docking, are widely applied to study interactions and
binding affinity of biological activity of proteins and peptides. However, restricted sampling of …

Review on the release mechanism and debittering technology of bitter peptides from protein hydrolysates

B Liu, N Li, F Chen, J Zhang, X Sun… - … Reviews in Food …, 2022 - Wiley Online Library
Recent scientific evidence indicates that protein hydrolysates contain bioactive peptides that
have potential benefits for human health. However, the bitter‐tasting hydrophobic peptides …

UniDL4BioPep: a universal deep learning architecture for binary classification in peptide bioactivity

Z Du, X Ding, Y Xu, Y Li - Briefings in Bioinformatics, 2023 - academic.oup.com
Identification of potent peptides through model prediction can reduce benchwork in wet
experiments. However, the conventional process of model buildings can be complex and …

BERT4Bitter: a bidirectional encoder representations from transformers (BERT)-based model for improving the prediction of bitter peptides

P Charoenkwan, C Nantasenamat, MM Hasan… - …, 2021 - academic.oup.com
Motivation The identification of bitter peptides through experimental approaches is an
expensive and time-consuming endeavor. Due to the huge number of newly available …

[HTML][HTML] Review on plant-derived bioactive peptides: biological activities, mechanism of action and utilizations in food development

H Fan, H Liu, Y Zhang, S Zhang, T Liu, D Wang - Journal of Future Foods, 2022 - Elsevier
Plant proteins are good alternative to animal sources in bioactive peptide production due to
their safety, low-cost, rich resources and easy for large scale production. The bioactivities of …

StackIL6: a stacking ensemble model for improving the prediction of IL-6 inducing peptides

P Charoenkwan, W Chiangjong… - Briefings in …, 2021 - academic.oup.com
The release of interleukin (IL)-6 is stimulated by antigenic peptides from pathogens as well
as by immune cells for activating aggressive inflammation. IL-6 inducing peptides are …

Algae as a potential source of protein meat alternatives

J Espinosa-Ramírez… - Frontiers in …, 2023 - frontiersin.org
With the rise of plant-based meat alternatives, there is a growing need for sustainable and
nutritious sources of protein. Alga is a rich protein source, and initial studies show that it can …

A TastePeptides-Meta system including an umami/bitter classification model Umami_YYDS, a TastePeptidesDB database and an open-source package …

Z Cui, Z Zhang, T Zhou, X Zhou, Y Zhang, H Meng… - Food Chemistry, 2023 - Elsevier
Taste peptides with umami/bitterness play a role in food attributes. However, the taste
mechanisms of peptides are not fully understood, and the identification of these peptides is …

Research progress in the screening and evaluation of umami peptides

L Qi, X Gao, D Pan, Y Sun, Z Cai… - … Reviews in Food …, 2022 - Wiley Online Library
Umami is an important element affecting food taste, and the development of umami peptides
is a topic of interest in food‐flavoring research. The existing technology used for traditional …

In-silico investigation of umami peptides with receptor T1R1/T1R3 for the discovering potential targets: A combined modeling approach

W Wang, Z Cui, M Ning, T Zhou, Y Liu - Biomaterials, 2022 - Elsevier
Umami, providing amino acids/peptides for animal growth, represents one of the major
attractive taste modalities. The biochemical and umami properties of peptide are both …