Apicomplexa are obligatory intracellular parasites that sense and actively invade host cells.
Invasion is a conserved process that relies on the timely and spatially controlled exocytosis …

Apicomplexan parasites comprise significant pathogens of humans, livestock and wildlife,
but also represent a diverse group of eukaryotes with interesting and unique cell biology …

The phylum Apicomplexa comprises important eukaryotic parasites that invade host tissues
and cells using a unique mechanism of gliding motility. Gliding is powered by actomyosin …

Examining host–pathogen interactions in animals can capture aspects of infection that are
obscured in cell culture. Using CRISPR-based screens, we functionally profile the entire …

Members of Apicomplexa are defined by apical cytoskeletal structures and secretory
organelles, tailored for motility, invasion and egress. Gliding is powered by actomyosin …

Apicomplexan parasites are a group of eukaryotic protozoans with diverse biology that have
affected human health like no other group of parasites. These obligate intracellular parasites …

Apicomplexan parasites secrete contents of the rhoptries, club-shaped organelles in the
apical region, into host cells to permit their invasion and establishment of infection. The …

Apicomplexan parasites have immense impacts on humanity, but their basic cellular
processes are often poorly understood. Where endocytosis occurs in these cells, how …

Apicomplexan parasites possess secretory organelles called rhoptries that undergo
regulated exocytosis upon contact with the host. This process is essential for the parasitic …

Myzozoans encompass apicomplexans and dinoflagellates that manifest diverse lifestyles in
highly varied environments. They show enormous propensity to employ different metabolic …