Doxorubicin—an agent with multiple mechanisms of anticancer activity
Doxorubicin (DOX) constitutes the major constituent of anti-cancer treatment regimens
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …
Nanoparticle surface functionalization: how to improve biocompatibility and cellular internalization
The use of nanoparticles (NP) in diagnosis and treatment of many human diseases,
including cancer, is of increasing interest. However, cytotoxic effects of NPs on cells and the …
including cancer, is of increasing interest. However, cytotoxic effects of NPs on cells and the …
[HTML][HTML] Ultrasmall gold nanoparticles in cancer diagnosis and therapy
Due to their lower systemic toxicity, faster kidney clearance and higher tumor accumulation,
ultrasmall gold nanoparticles (less than 10 nm in diameter) have been proved to be …
ultrasmall gold nanoparticles (less than 10 nm in diameter) have been proved to be …
Combined cytotoxic chemotherapy and immunotherapy of cancer: modern times
Monoclonal antibodies targeting programmed cell death 1/programmed cell death ligand 1
(PD-1/PD-L1) immune checkpoints have improved the treatments of cancers. However, not …
(PD-1/PD-L1) immune checkpoints have improved the treatments of cancers. However, not …
Synergic effects of nanoparticles-mediated hyperthermia in radiotherapy/chemotherapy of cancer
The conventional cancer treatment modalities such as radiotherapy and chemotherapy
suffer from several limitations; hence, their efficiency needs to be improved with other …
suffer from several limitations; hence, their efficiency needs to be improved with other …
Antibody‐incorporated nanomedicines for cancer therapy
Antibody‐based cancer therapy, one of the most significant therapeutic strategies, has
achieved considerable success and progress over the past decades. Nevertheless …
achieved considerable success and progress over the past decades. Nevertheless …
ROS-based dynamic therapy synergy with modulating tumor cell-microenvironment mediated by inorganic nanomedicine
X Zhong, X Wang, J Li, J Hu, L Cheng… - Coordination Chemistry …, 2021 - Elsevier
Dynamic therapy (DT) by in situ ROS generation is emerging as an attractive therapeutic
modality with potential to treat deep-seated tumors, avoiding side effects to healthy tissues …
modality with potential to treat deep-seated tumors, avoiding side effects to healthy tissues …
Next-generation engineered nanogold for multimodal cancer therapy and imaging: a clinical perspectives
M Alle, G Sharma, SH Lee, JC Kim - Journal of nanobiotechnology, 2022 - Springer
Cancer is one of the significant threats to human life. Although various latest technologies
are currently available to treat cancer, it still accounts for millions of death each year …
are currently available to treat cancer, it still accounts for millions of death each year …
Recent progress, perspectives, and issues of engineered PD-L1 regulation nano-system to better cure tumor: A review
Z Zhou, H Wang, J Li, X Jiang, Z Li, J Shen - International Journal of …, 2024 - Elsevier
Currently, immune checkpoint blockade (ICB) therapies that target the programmed cell
death ligand-1 (PD-L1) have been used as revolutionary cancer treatments in the clinic …
death ligand-1 (PD-L1) have been used as revolutionary cancer treatments in the clinic …
Gold nanoparticles: construction for drug delivery and application in cancer immunotherapy
H Huang, R Liu, J Yang, J Dai, S Fan, J Pi, Y Wei… - Pharmaceutics, 2023 - mdpi.com
Cancer immunotherapy is an innovative treatment strategy to enhance the ability of the
immune system to recognize and eliminate cancer cells. However, dose limitations, low …
immune system to recognize and eliminate cancer cells. However, dose limitations, low …