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Oxindole: A chemical prism carrying plethora of therapeutic benefits
Oxindole has emerged as a valuable scaffold in medicinal chemistry possessing diverse
range of pharmacological activities. Its value has further been increased by its natural …
range of pharmacological activities. Its value has further been increased by its natural …
Formulation, structure, and applications of therapeutic and amino acid-based deep eutectic solvents: An overview
In the design of greener chemicals, deep eutectic solvents (DESs) are considered as one of
the most versatile alternative media with widespread applications. DESs have the …
the most versatile alternative media with widespread applications. DESs have the …
Bis-and trisindolylmethanes (BIMs and TIMs)
The indole ring system is present in many natural products, pharmaceuticals,
agrochemicals, and other compounds of importance. 1–8 The indole unit forms the basis for …
agrochemicals, and other compounds of importance. 1–8 The indole unit forms the basis for …
Effective synthesis and biological evaluation of natural and designed bis (indolyl) methanes via taurine-catalyzed green approach
An ecofriendly, inexpensive, and efficient route for synthesizing 3, 3′-bis (indolyl) methanes
(BIMs) and their derivatives was carried out by an electrophilic substitution reaction of indole …
(BIMs) and their derivatives was carried out by an electrophilic substitution reaction of indole …
Recent advances in diversity oriented synthesis through isatin‐based multicomponent reactions
Y Liu, H Wang, J Wan - Asian Journal of Organic Chemistry, 2013 - Wiley Online Library
Isatins are well‐known carbonyl electrophiles which allow a vast number of reactions
initiated by nucleophilic attack on the C3 carbonyl group when used as starting materials …
initiated by nucleophilic attack on the C3 carbonyl group when used as starting materials …
Molecular iodine-catalyzed multicomponent reactions: an efficient catalyst for organic synthesis
YM Ren, C Cai, RC Yang - RSC advances, 2013 - pubs.rsc.org
The multicomponent reactions (MCRs) consist of two or more synthetic steps which are
carried out without isolation of any intermediate thus reducing time, saving money, energy …
carried out without isolation of any intermediate thus reducing time, saving money, energy …
Substrate-controlled regioselective arylations of 2-indolylmethanols with indoles: Synthesis of bis (indolyl) methane and 3, 3′-bisindole derivatives
YY He, XX Sun, GH Li, GJ Mei, F Shi - The Journal of Organic …, 2017 - ACS Publications
A substrate-controlled regioselective arylation of 2-indolylmethanols with indoles has been
established, which efficiently afforded bis (indolyl) methane and 3, 3′-bisindole derivatives …
established, which efficiently afforded bis (indolyl) methane and 3, 3′-bisindole derivatives …
Synthesis of 3, 3-diindolyl oxyindoles efficiently catalysed by FeCl3 and their in vitro evaluation for anticancer activity
A Kamal, YVV Srikanth, MNA Khan, TB Shaik… - Bioorganic & medicinal …, 2010 - Elsevier
A simple and highly efficient method has been developed for the synthesis of 3, 3-diindolyl
oxyindoles by the reaction of indoles with isatin or 5-fluoro isatin using a catalytic amount …
oxyindoles by the reaction of indoles with isatin or 5-fluoro isatin using a catalytic amount …
Design for carbon–carbon bond forming reactions under ambient conditions
G Brahmachari - RSC advances, 2016 - pubs.rsc.org
The carbon–carbon (C–C) bond forms the 'backbone'of nearly every organic molecule, and
lies at the heart of the chemical sciences! This transformation has always been one of the …
lies at the heart of the chemical sciences! This transformation has always been one of the …
Synthesis, α-glucosidase inhibition, α-amylase inhibition, and molecular docking studies of 3, 3-di (indolyl) indolin-2-ones
Abstract The synthesized 3, 3-di (indolyl) indolin-2-ones 1a-p showed desired higher α-
glucosidase inhibitory activities and lower α-amylase inhibitory activities than standard drug …
glucosidase inhibitory activities and lower α-amylase inhibitory activities than standard drug …