Role of EGFR in the Nervous System

R Romano, C Bucci - Cells, 2020 - mdpi.com
Epidermal growth factor receptor (EGFR) is the first discovered member of the receptor
tyrosine kinase superfamily and plays a fundamental role during embryogenesis and in …

Epidermal growth factor, from gene organization to bedside

F Zeng, RC Harris - Seminars in cell & developmental biology, 2014 - Elsevier
In 1962, epidermal growth factor (EGF) was discovered by Dr. Stanley Cohen while studying
nerve growth factor (NGF). It was soon recognized that EGF is the prototypical member of a …

Combined analysis of dissimilar promoter accessibility and gene expression profiles identifies tissue-specific genes and actively repressed networks

RR Starks, A Biswas, A Jain, G Tuteja - Epigenetics & chromatin, 2019 - Springer
Background The assay for transposase-accessible chromatin (ATAC-seq) is a powerful
method to examine chromatin accessibility. While many studies have reported a positive …

The role of astrocytes in the development of the cerebellum

APB Araujo, R Carpi-Santos, FCA Gomes - The Cerebellum, 2019 - Springer
Astrocytes, initially described as merely support cells, are now known as a heterogeneous
population of cells actively involved in a variety of biological functions such as: neuronal …

Modulation of pathological pain by epidermal growth factor receptor

JP Borges, K Mekhail, GD Fairn… - Frontiers in …, 2021 - frontiersin.org
Chronic pain has been widely recognized as a major public health problem that impacts
multiple aspects of patient quality of life. Unfortunately, chronic pain is often resistant to …

Local epidermal growth factor delivery using nanopillared chitosan–gelatin films for melanogenesis and wound healing

S Altuntas, HK Dhaliwal, AE Radwan, M Amiji… - Biomaterials …, 2023 - pubs.rsc.org
Epidermal growth factor (EGF) is required for various regulations of skin tissue including
wound healing; however, it has limited stability due to the physicochemical conditions of the …

A novel human pluripotent stem cell-derived neural crest model of treacher collins syndrome shows defects in cell death and migration

F Serrano, WG Bernard, A Granata, D Iyer… - Stem Cells and …, 2019 - liebertpub.com
The neural crest (NC) is a transient multipotent cell population present during embryonic
development. The NC can give rise to multiple cell types and is involved in a number of …

[HTML][HTML] The potential role of physical exercise in the treatment of epilepsy

RM Arida, FA Scorza, SG da Silva, SC Schachter… - Epilepsy & Behavior, 2010 - Elsevier
The beneficial effects of exercise for people with epilepsy, including reduction of seizure
susceptibility, improvement of quality of life, reduction of anxiety and depression, and better …

BDNF Promotes EGF-Induced Proliferation and Migration of Human Fetal Neural Stem/Progenitor Cells via the PI3K/Akt Pathwa

Q Zhang, G Liu, Y Wu, H Sha, P Zhang, J Jia - Molecules, 2011 - mdpi.com
Neurogenesis is a complex process, which contributes to the ability of the adult brain to
function normally and adapt to diseases. Epidermal growth factor (EGF) is known to play an …

Comparative evaluation of divergent concoction of NGF, BDNF, EGF, and FGF growth factor's role in enhancing neuronal differentiation of adipose-derived …

P Choudhary, A Gupta, SK Gupta, S Dwivedi… - International Journal of …, 2024 - Elsevier
Abstract MSCs (Mesenchymal Stem Cells) can differentiate into various lineages, including
neurons and glial cells. In the past few decades, MSCs have been well explored in the …