Multiscale simulations of biological membranes: the challenge to understand biological phenomena in a living substance
Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …
composition and structure, functional over a wide range of time scales, and characterized by …
Non-HDL-cholesterol and apolipoprotein B compared with LDL-cholesterol in atherosclerotic cardiovascular disease risk assessment
SS Carr, AJ Hooper, DR Sullivan, JR Burnett - Pathology, 2019 - Elsevier
Low density lipoprotein (LDL) is the predominant atherogenic lipoprotein particle in the
circulation. Conventionally, a fasting lipid profile has been used for atherosclerotic …
circulation. Conventionally, a fasting lipid profile has been used for atherosclerotic …
Concepts and methods of solid-state NMR spectroscopy applied to biomembranes
TR Molugu, S Lee, MF Brown - Chemical reviews, 2017 - ACS Publications
Concepts of solid-state NMR spectroscopy and applications to fluid membranes are
reviewed in this paper. Membrane lipids with 2H-labeled acyl chains or polar head groups …
reviewed in this paper. Membrane lipids with 2H-labeled acyl chains or polar head groups …
A dual apolipoprotein C-II mimetic–apolipoprotein C-III antagonist peptide lowers plasma triglycerides
Recent genetic studies have established that hypertriglyceridemia (HTG) is causally related
to cardiovascular disease, making it an active area for drug development. We describe a …
to cardiovascular disease, making it an active area for drug development. We describe a …
Computational studies of lipid droplets
Lipid droplets (LDs) are intracellular organelles whose primary function is energy storage.
Known to emerge from the endoplasmic reticulum (ER) bilayer, LDs have a unique structure …
Known to emerge from the endoplasmic reticulum (ER) bilayer, LDs have a unique structure …
Therapeutic potential of ApoE-mimetic peptides in CNS disorders: Current perspective
The prevalence and burden of CNS disorders are increasing significantly due to the
increase in life span and population. The contemporary need in CNS drug discovery is to …
increase in life span and population. The contemporary need in CNS drug discovery is to …
The surface and hydration properties of lipid droplets
Lipid droplets (LDs) are energy storage organelles composed of neutral lipids, such as
triacylglycerol (TG) and sterol esters, surrounded by a phospholipid (PL) monolayer. Their …
triacylglycerol (TG) and sterol esters, surrounded by a phospholipid (PL) monolayer. Their …
Stressed lipid droplets: How neutral lipids relieve surface tension and membrane expansion drives protein association
Lipid droplets (LDs) are intracellular storage organelles composed of neutral lipids, such as
triacylglycerol (TG), surrounded by a phospholipid (PL) monolayer decorated with specific …
triacylglycerol (TG), surrounded by a phospholipid (PL) monolayer decorated with specific …
[HTML][HTML] Molecular dynamics simulations of lipid nanodiscs
A lipid nanodisc is a discoidal lipid bilayer stabilized by proteins, peptides, or polymers on its
edge. Nanodiscs have two important connections to structural biology. The first is associated …
edge. Nanodiscs have two important connections to structural biology. The first is associated …
Physical characterization of triolein and implications for its role in lipid droplet biogenesis
Lipid droplets (LDs) are neutral lipid-storing organelles surrounded by a phospholipid (PL)
monolayer. At present, how LDs are formed in the endoplasmic reticulum (ER) bilayer is …
monolayer. At present, how LDs are formed in the endoplasmic reticulum (ER) bilayer is …